Dietary fat quality indices and risk of pre-diabetes and type 2 diabetes mellitus: Tehran Lipid and Glucose Study.

IF 3 3区医学 Q2 NUTRITION & DIETETICS

Public Health Nutrition Pub Date : 2024-12-09 DOI:10.1017/S1368980024001216

Zahra Gaeini, Sevda Alvirdizadeh, Somayeh Hosseinpour-Niazi, Parvin Mirmiran, Fereidoun Azizi

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引用次数: 0

Abstract

Objective: To assess associations between dietary fat quality indices and risk of pre-diabetes and type 2 diabetes mellitus (T2DM) among Iranian adults.

Design: Daily intakes of fatty acids were estimated using a validated FFQ with 168 food items. Adjusted hazard ratios (HR) and 95 % CI for pre-diabetes and T2DM were calculated across tertile categories of dietary fat quality indices including the atherogenic index, thrombogenic index, health-promoting index, ratio of PUFA to SFA (PUFA:SFA) and ratio of hypo- and hypercholesterolaemia (h:H).

Setting: Tehran Lipid and Glucose Study.

Participants: Iranian men and women.

Results: The mean (sd) age of the 2042 pre-diabetes-free participants in pre-diabetes analysis was 38·84 (12·97), and 55·2 % were women. In T2DM analysis, the mean (sd) age of the 2295 T2DM-free participants was 40·06 (13·42), and 54·6 % of them were women. In the crude model, the PUFA:SFA ratio was positively associated with T2DM incidence (HR = 1·43; 95 % CI 1·04, 1·98). However, after adjustment for confounding variables, there were no significant associations between dietary fat quality indices and risk of pre-diabetes and T2DM.

Conclusions: We found no significant association between fat quality indices and risk of pre-diabetes and T2DM. Further prospective and clinical trial studies are needed to clarify the issue.

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饮食脂肪质量指标与糖尿病前期和2型糖尿病的风险：德黑兰脂质和葡萄糖研究。

目的：评估伊朗成年人的饮食脂肪质量指数（FQI）与糖尿病前期和 2 型糖尿病（T2DM）风险之间的关系：评估伊朗成年人的膳食脂肪质量指数（FQI）与糖尿病前期和 2 型糖尿病（T2DM）风险之间的关系：设计：使用经过验证的食物频率问卷估算每日脂肪酸摄入量，问卷中包含 168 种食物。根据膳食 FQI 的三等分类别，包括致动脉粥样硬化指数（AI）、血栓形成指数（TI）、健康促进指数（HPI）、多不饱和脂肪酸与饱和脂肪酸之比（PUFA/SFA）以及低胆固醇血症与高胆固醇血症之比（h/H），计算糖尿病前期和 T2DM 的调整后危险比（HRs）和 95% 置信区间（CIs）：德黑兰血脂和血糖研究：结果在糖尿病前期分析中，2042 名未患糖尿病的参与者的平均年龄（±SD）为 38.84（12.97）岁，55.2% 为女性。在 T2DM 分析中，2295 名无 T2DM 患者的平均年龄（±SD）为 40.06（13.42）岁，其中 54.6% 为女性。在粗略模型中，PUFA/SFA比率与T2DM发病率呈正相关（HR=1.43，95% CI：1.04-1.98）。然而，在对混杂变量进行调整后，膳食 FQI 与糖尿病前期和 T2DM 风险之间并无显著关联：结论：我们发现，膳食纤维质量指数与糖尿病前期和 T2DM 风险之间没有明显关联。结论：我们发现膳食纤维质量指数与糖尿病前期和 T2DM 风险之间没有明显关联，需要进一步的前瞻性和临床试验研究来澄清这一问题。

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来源期刊

Public Health Nutrition 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.10

自引率

6.20%

发文量

521

审稿时长

3 months

期刊介绍： Public Health Nutrition provides an international peer-reviewed forum for the publication and dissemination of research and scholarship aimed at understanding the causes of, and approaches and solutions to nutrition-related public health achievements, situations and problems around the world. The journal publishes original and commissioned articles, commentaries and discussion papers for debate. The journal is of interest to epidemiologists and health promotion specialists interested in the role of nutrition in disease prevention; academics and those involved in fieldwork and the application of research to identify practical solutions to important public health problems.