Health-related quality of life and its factors in Chinese people with depression and anxiety: A national multi-center cross-sectional study.

IF 4.9 2区 医学 Q1 CLINICAL NEUROLOGY
Ting Wang, Shuyong Zhang, Yating Yang, Biqi Zu, Chunying Pan, Juan Yin
{"title":"Health-related quality of life and its factors in Chinese people with depression and anxiety: A national multi-center cross-sectional study.","authors":"Ting Wang, Shuyong Zhang, Yating Yang, Biqi Zu, Chunying Pan, Juan Yin","doi":"10.1016/j.jad.2024.12.004","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The prevalence of depression and anxiety in Chinese population has been increasing in recently years, yet the health-related quality of life (HRQoL) of people with depression and anxiety remains unclear.</p><p><strong>Objective: </strong>To evaluate the HRQoL of individuals with depression and anxiety in China and to explore the factors influencing it.</p><p><strong>Methods: </strong>The study population was divided into a depressed group and non-depressed group, as well as an anxious group and non-anxious group. The EuroQol five-dimensional five-level questionnaire (EQ-5D-5L) was used to assess HRQoL in these individuals. Regression with the least absolute shrinkage and selection operator (Lasso) was applied separately to the datasets of the depressed and anxious populations for variable selection. A Tobit regression model was then used to analyze the relationship between various influencing factors and HRQoL in individuals with depression and anxiety.</p><p><strong>Results: </strong>A total of 7920 valid samples were collected from the PBICR database, including 1406 individuals with depression and 933 with anxiety. The HRQoL for individuals with depression and anxiety was estimated at 80.38 ± 17.17 and 80 ± 17.57, respectively. Among those with depression, a significant decrease in HRQoL was observed in individuals with debt (P = 0.021) and ex-smokers (P = 0.022) compared to their control groups. Health literacy (P < 0.001) and self-efficacy (P = 0.008) were identified as significant factors influencing HRQoL. For participants with anxiety, HRQoL was also lower among individuals with debt (P = 0.047) and ex-smokers (P = 0.033) compared to their control groups. Health literacy (P < 0.001) was a significant factor influencing HRQoL. Among individuals with depression (P = 0.006) and anxiety (P = 0.001), males had significantly higher HRQoL than females.</p><p><strong>Conclusion: </strong>Common factors influencing the HRQoL of both individuals with depression and those with anxiety include debt, gender, smoking status, and health literacy. Additionally, self-efficacy is a significant factor affecting the HRQoL of individuals with depression.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"241-250"},"PeriodicalIF":4.9000,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of affective disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jad.2024.12.004","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: The prevalence of depression and anxiety in Chinese population has been increasing in recently years, yet the health-related quality of life (HRQoL) of people with depression and anxiety remains unclear.

Objective: To evaluate the HRQoL of individuals with depression and anxiety in China and to explore the factors influencing it.

Methods: The study population was divided into a depressed group and non-depressed group, as well as an anxious group and non-anxious group. The EuroQol five-dimensional five-level questionnaire (EQ-5D-5L) was used to assess HRQoL in these individuals. Regression with the least absolute shrinkage and selection operator (Lasso) was applied separately to the datasets of the depressed and anxious populations for variable selection. A Tobit regression model was then used to analyze the relationship between various influencing factors and HRQoL in individuals with depression and anxiety.

Results: A total of 7920 valid samples were collected from the PBICR database, including 1406 individuals with depression and 933 with anxiety. The HRQoL for individuals with depression and anxiety was estimated at 80.38 ± 17.17 and 80 ± 17.57, respectively. Among those with depression, a significant decrease in HRQoL was observed in individuals with debt (P = 0.021) and ex-smokers (P = 0.022) compared to their control groups. Health literacy (P < 0.001) and self-efficacy (P = 0.008) were identified as significant factors influencing HRQoL. For participants with anxiety, HRQoL was also lower among individuals with debt (P = 0.047) and ex-smokers (P = 0.033) compared to their control groups. Health literacy (P < 0.001) was a significant factor influencing HRQoL. Among individuals with depression (P = 0.006) and anxiety (P = 0.001), males had significantly higher HRQoL than females.

Conclusion: Common factors influencing the HRQoL of both individuals with depression and those with anxiety include debt, gender, smoking status, and health literacy. Additionally, self-efficacy is a significant factor affecting the HRQoL of individuals with depression.

求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of affective disorders
Journal of affective disorders 医学-精神病学
CiteScore
10.90
自引率
6.10%
发文量
1319
审稿时长
9.3 weeks
期刊介绍: The Journal of Affective Disorders publishes papers concerned with affective disorders in the widest sense: depression, mania, mood spectrum, emotions and personality, anxiety and stress. It is interdisciplinary and aims to bring together different approaches for a diverse readership. Top quality papers will be accepted dealing with any aspect of affective disorders, including neuroimaging, cognitive neurosciences, genetics, molecular biology, experimental and clinical neurosciences, pharmacology, neuroimmunoendocrinology, intervention and treatment trials.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信