Long term noninvasive respiratory support in children with OSA-I and OSA-II: Data of a nation-wide study

IF 3.8 2区医学 Q1 CLINICAL NEUROLOGY

Sleep medicine Pub Date : 2025-02-01 DOI:10.1016/j.sleep.2024.11.039

Chiara Tommesani , Sonia Khirani , Alessandro Amaddeo , Bruno Massenavette , Priscille Bierme , Jessica Taytard , Nathalie Stremler , Melisande Baravalle-Einaudi , Julie Mazenq , Iulia Ioan , Cyril Schweitzer , Marie Emilie Lampin , Alexandra Binoche , Clemence Mordacq , Jean Bergounioux , Blaise Mbieleu , Robert Rubinsztajn , Elodie Sigur , Geraldine Labouret , Aline Genevois , Brigitte Fauroux

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引用次数: 0

Abstract

Purpose

The aim of the study was to analyze the characteristics of otherwise healthy children with obstructive sleep apnea (OSA; OSA-I) and children with OSA and non-syndromic obesity (OSA-II) treated with long term continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) in 2019 in France.

Methods

Data were collected from a national survey on paediatric home noninvasive ventilatory support. CPAP/NIV initiation criteria and duration, age at CPAP/NIV initiation, equipment used and CPAP/NIV settings, and objective compliance were analyzed.

Results

Patients with OSA-I and OSA-II represented 6 % (n = 84, 71 % males) and 10 % (n = 144, 72 % males) of the national cohort, respectively. The apnea-hypopnea index (63 % vs 76 %), alone or combined with nocturnal gas exchange (25 % vs 21 %, for OSA-II and OSA-I patients respectively) were used as initiation criteria of CPAP/NIV. OSA-II patients were older at CPAP/NIV initiation (mean age 11.0 ± 4.0 vs 6.8 ± 4.5 years, p < 0.001) and were treated for a longer time (2.3 ± 2.6 vs 1.3 ± 1.5 years, p = 0.008) than OSA-I patients. NIV was used in 6 % of OSA-I patients and 13 % of OSA-II patients (p = 0.142). Both groups used preferentially a nasal mask. Mean CPAP level was higher in OSA-II patients as compared to OSA-I patients (8.7 ± 2.0 vs 7.7 ± 2.4 cmH₂O, p = 0.02). Objective compliance was comparable (mean use 6.8 ± 2.6 vs 5.9 ± 3.0 h/night in OSA-I and OSA-II, respectively, p = 0.054).

Conclusion

Six and 10 % of children treated with long term CPAP/NIV in France in 2019 had OSA-I and OSA-II, respectively. Both groups were preferentially treated with CPAP and were comparable except for age, with OSA-II patients being older at CPAP/NIV initiation.

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OSA-I和OSA-II患儿的长期无创呼吸支持：一项全国性研究的数据

目的：本研究的目的是分析其他健康的阻塞性睡眠呼吸暂停（OSA）儿童的特征；2019年，在法国，OSA- i型和OSA- ii型儿童接受长期持续气道正压通气（CPAP）或无创通气（NIV）治疗。方法：收集全国儿童家庭无创通气支持调查数据。分析CPAP/NIV启动标准和持续时间、CPAP/NIV启动时的年龄、使用的设备和CPAP/NIV设置以及客观依从性。结果：osa - 1和OSA-II患者分别占全国队列的6% （n = 84，男性71%）和10% （n = 144，男性72%）。呼吸暂停-低通气指数（63% vs 76%），单独或联合夜间气体交换（分别为25% vs 21%， OSA-II和OSA-I患者）被用作CPAP/NIV的起始标准。OSA-II型患者在CPAP/NIV启动时年龄较大（平均年龄11.0±4.0岁vs 6.8±4.5岁，p 2O, p = 0.02）。客观依从性具有可比性（OSA-I和OSA-II患者的平均使用时间分别为6.8±2.6和5.9±3.0小时/晚，p = 0.054）。结论：2019年法国接受长期CPAP/NIV治疗的儿童中，分别有6%和10%患有OSA-I和OSA-II。两组均优先接受CPAP治疗，除年龄外具有可比性，OSA-II患者在CPAP/NIV开始时年龄较大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sleep medicine 医学-临床神经学

CiteScore

8.40

自引率

6.20%

发文量

1060

审稿时长

49 days

期刊介绍： Sleep Medicine aims to be a journal no one involved in clinical sleep medicine can do without. A journal primarily focussing on the human aspects of sleep, integrating the various disciplines that are involved in sleep medicine: neurology, clinical neurophysiology, internal medicine (particularly pulmonology and cardiology), psychology, psychiatry, sleep technology, pediatrics, neurosurgery, otorhinolaryngology, and dentistry. The journal publishes the following types of articles: Reviews (also intended as a way to bridge the gap between basic sleep research and clinical relevance); Original Research Articles; Full-length articles; Brief communications; Controversies; Case reports; Letters to the Editor; Journal search and commentaries; Book reviews; Meeting announcements; Listing of relevant organisations plus web sites.