Effect of Composition of Nonionic and Cationic Copolymers of Alkoxyoligo(ethylene glycol) Methacrylates and Dodecyl Methacrylate on Their Properties in Solutions

IF 1 4区化学 Q4 POLYMER SCIENCE

Polymer Science, Series A Pub Date : 2024-09-29 DOI:10.1134/S0965545X24600844

D. M. Kamorin, O. A. Kazantsev, A. S. Simagin, D. V. Orekhov, M. V. Savinova, I. R. Arifullin, A. P. Sivokhin

{"title":"Effect of Composition of Nonionic and Cationic Copolymers of Alkoxyoligo(ethylene glycol) Methacrylates and Dodecyl Methacrylate on Their Properties in Solutions","authors":"D. M. Kamorin, O. A. Kazantsev, A. S. Simagin, D. V. Orekhov, M. V. Savinova, I. R. Arifullin, A. P. Sivokhin","doi":"10.1134/S0965545X24600844","DOIUrl":null,"url":null,"abstract":"The properties of nonionic and cationic molecular brushes, the copolymers of methoxy- or higher n-alkoxyoligo(ethylene glycol) methacrylates with dodecyl methacrylate and terpolymers additionally containing cationic units of N-methacryloylaminopropyl-N,N-dimethyl-N-propylammonium bromide, in water, organic solvents, and two-phase systems water–hydrocarbon and aqueous saline solution–hydrocarbon have been studied. Effect of the composition of molecular brushes, calculated values of their hydrophilic–hydrophobic balance, solvent polarity, and temperature on the solubility of the polymers, micellization (critical micelle concentration and sizes of macromolecular associates), phase transition conditions, and interfacial activity is estimated. A set of properties of the presented molecular brushes allows their inclusion in a number of potential polymeric micellar nanocontainers for controlled drug delivery into the body.","PeriodicalId":738,"journal":{"name":"Polymer Science, Series A","volume":"66 3","pages":"315 - 326"},"PeriodicalIF":1.0000,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer Science, Series A","FirstCategoryId":"1","ListUrlMain":"https://link.springer.com/article/10.1134/S0965545X24600844","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}

引用次数: 0

Abstract

The properties of nonionic and cationic molecular brushes, the copolymers of methoxy- or higher n-alkoxyoligo(ethylene glycol) methacrylates with dodecyl methacrylate and terpolymers additionally containing cationic units of N-methacryloylaminopropyl-N,N-dimethyl-N-propylammonium bromide, in water, organic solvents, and two-phase systems water–hydrocarbon and aqueous saline solution–hydrocarbon have been studied. Effect of the composition of molecular brushes, calculated values of their hydrophilic–hydrophobic balance, solvent polarity, and temperature on the solubility of the polymers, micellization (critical micelle concentration and sizes of macromolecular associates), phase transition conditions, and interfacial activity is estimated. A set of properties of the presented molecular brushes allows their inclusion in a number of potential polymeric micellar nanocontainers for controlled drug delivery into the body.

Abstract Image

查看原文本刊更多论文

烷基氧基低聚（乙二醇）甲基丙烯酸酯和甲基丙烯酸十二酯非离子和阳离子共聚物组成对溶液性能的影响

研究了非离子和阳离子分子刷、甲氧基或更高的n-烷氧基低聚（乙二醇）甲基丙烯酸酯与甲基丙烯酸十二酯的共聚物以及另外含有n-甲基丙烯酰氨基丙基- n、n-二甲基- n-丙基溴化铵阳离子单元的三元聚合物在水、有机溶剂、水-烃和盐水-烃两相体系中的性能。估计了分子刷的组成、亲疏水平衡的计算值、溶剂极性和温度对聚合物的溶解度、胶束化（大分子缔合物的临界胶束浓度和大小）、相变条件和界面活性的影响。所提出的分子刷的一系列特性允许它们包含在许多潜在的聚合物胶束纳米容器中，用于控制药物输送到体内。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Polymer Science, Series A 化学-高分子科学

CiteScore

1.70

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： Polymer Science, Series A is a journal published in collaboration with the Russian Academy of Sciences. Series A includes experimental and theoretical papers and reviews devoted to physicochemical studies of the structure and properties of polymers (6 issues a year). All journal series present original papers and reviews covering all fundamental aspects of macromolecular science. Contributions should be of marked novelty and interest for a broad readership. Articles may be written in English or Russian regardless of country and nationality of authors. All manuscripts are peer reviewed. Online submission via Internet to the Series A, B, and C is available at http://polymsci.ru.