Reproductive mechanisms, pathologies, and health inclusivity: insights from the 2023 Annual Meeting of the Society for Reproductive Biology.

Abstract

In 2023, the Society for Reproductive Biology met in Brisbane to deliver its largest scientific program to date. Herein, we detail key areas of notable discovery across the reproductive biology and fertility landscapes, as well as pressing areas that require further research. Specifically, we focus on five key themes: the cellular basis of reproduction; environmental impacts on reproduction; inclusivity in reproductive health; reproductive cancers; and evolution of reproduction mechanisms. Highlights included the utility of organism models, such as using fruit flies to model human genetic disease, and the development of new blastocyst models; the impact of elevated temperature and endocrine-disrupting chemicals on the germline, sex organ development, and fertility in mammals; how we can improve the inclusivity of transgender and Pacific Rainbow+ people in reproductive health; novel insights in reproductive cancer pathogenesis and inhibitor treatments; and the evolution of the sex chromosomes and sex determination across animals. The breadth of topics covered underscores the far-reaching impacts of reproduction and its related processes across life, health, and wellbeing, as well as for food production and the economy.