Surgical identification of brain tumour margins through impedance monitoring and electrocorticography and the potential for their combined use: A systematic review.

IF 2.5 3区医学 Q2 CLINICAL NEUROLOGY

Neurosurgical Review Pub Date : 2024-12-06 DOI:10.1007/s10143-024-03134-0

Ariadni Georgiannakis, Christopher A R Chapman, Dimitrios Paraskevopoulos

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引用次数: 0

Abstract

Context: Primary central nervous system tumours have poor survival outcomes. Surgery, the first-line treatment, presents technical limitations, such as visualising the whole tumour border. Intracranial impedance monitoring and electrocorticography techniques provide insights into the local field potential characteristics, resistance and capacitance properties of brain tissue. We hypothesised that measurements obtained by either modality can distinguish between tumour and healthy brain tissue intraoperatively.

Methods: A "Preferred Reporting Items for Systematic Reviews and Meta-Analyses" (PRISMA)-compliant systematic review was conducted, searching PubMed, Ovid, Scopus, Cochrane and Web of Science. Studies on electrocorticography and impedance monitoring in patients with brain tumours were included. Data on patient demographics, technical details, obtained results and safety were extracted and analysed in Excel.

Results: Eighteen studies involving 286 patients in total were identified. Ten impedance studies showed that brain tumour tissue has significantly different values than healthy tissue, while its resistivity varies, being either higher or lower. Eight electrocorticography studies indicated increased high gamma power and altered connectivity in tumour tissue. No studies integrated impedance monitoring and electrocorticography in one device.

Conclusion: Impedance and electrocorticography measurements have the potential of differentiating between tumour and unaffected issues intra-operatively. Larger studies with standardised protocols are needed to validate these findings. Additionally, the combination of these two modalities has the potential for improved specificity with a single device. Future research should explore the role of these modalities in enhancing tumour margin identification across different tumour subtypes and in improving survival outcomes.

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来源期刊

Neurosurgical Review 医学-临床神经学

CiteScore

5.60

自引率

7.10%

发文量

191

审稿时长

6-12 weeks

期刊介绍： The goal of Neurosurgical Review is to provide a forum for comprehensive reviews on current issues in neurosurgery. Each issue contains up to three reviews, reflecting all important aspects of one topic (a disease or a surgical approach). Comments by a panel of experts within the same issue complete the topic. By providing comprehensive coverage of one topic per issue, Neurosurgical Review combines the topicality of professional journals with the indepth treatment of a monograph. Original papers of high quality are also welcome.