Patterns and Outcomes of Pediatric Uveitis in a University-Based Tertiary Referral Center in Riyadh, Saudi Arabia.

IF 2.6 4区医学 Q2 OPHTHALMOLOGY

Ocular Immunology and Inflammation Pub Date : 2024-12-05 DOI:10.1080/09273948.2024.2435470

Abdulrahman F AlBloushi, Sulaiman M AlTariqi, Ruba Saleh Alghofaili, Priscilla W Gikandi, Ahmed M Abu El-Asrar

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Abstract

Purpose: To investigate the patterns and outcomes of pediatric uveitis.

Methods: Retrospective review of patients with uveitis in pediatric age group.

Results: A total of 184 patients (335 eyes) were included. There were 96 (52.2%) boys and 88 (47.8%) girls, with a mean age of 12.8 ± 3.4 years at presentation. Panuveitis was most common (55.2%), followed by anterior uveitis (29.6%), intermediate uveitis (12.2%) and posterior uveitis (3%). Uveitis was non-granulomatous in 71% and non-infectious in 94.6% of the eyes. The most identifiable specific diagnoses were Vogt-Koyanagi-Harada (VKH) disease (21.2%), juvenile idiopathic arthritis (6.5%), sarcoidosis (4.3%), and presumed tuberculous uveitis (3.3%). After 1-year follow-up, 85.4% of the eyes achieved visual acuity of 20/40 or better.

Conclusions: The most common anatomic diagnosis was panuveitis. VKH disease was the most frequently diagnosed entity.

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沙特阿拉伯利雅得一所大学三级转诊中心儿童葡萄膜炎的模式和结果。

目的：探讨小儿葡萄膜炎的发病模式及预后。方法：对儿童年龄组葡萄膜炎患者进行回顾性分析。结果：共纳入184例（335只眼）。男96例（52.2%），女88例（47.8%），平均发病年龄12.8±3.4岁。最常见的是全葡萄膜炎（55.2%），其次是前葡萄膜炎（29.6%）、中间葡萄膜炎（12.2%）和后葡萄膜炎（3%）。葡萄膜炎非肉芽肿性占71%，非感染性占94.6%。最可识别的特异性诊断为Vogt-Koyanagi-Harada （VKH）病（21.2%）、青少年特发性关节炎（6.5%）、结节病（4.3%）和推定的结核性葡萄膜炎（3.3%）。经过1年的随访，85.4%的眼睛视力达到20/40以上。结论：最常见的解剖诊断为全葡萄膜炎。VKH病是最常见的诊断实体。

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.