Astragaloside IV inhibits vascular calcification through estrogen receptor alpha.

IF 2.4 4区 医学 Q3 GERIATRICS & GERONTOLOGY
Michiko Nanao-Hamai, Bo-Kyung Son, Sumito Ogawa, Masahiro Akishita
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引用次数: 0

Abstract

Astragaloside IV (As-IV), a key component of traditional Japanese Hozai tonics, has a steroid skeleton like estrogen. It inhibits vascular calcification via estrogen receptor α, offering cardiovascular benefits. However, its estrogen-like properties promote breast cancer cell proliferation. Targeted research is needed to optimize cardiovascular preventive effects without adverse effects.

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来源期刊
CiteScore
5.50
自引率
6.10%
发文量
189
审稿时长
4-8 weeks
期刊介绍: Geriatrics & Gerontology International is the official Journal of the Japan Geriatrics Society, reflecting the growing importance of the subject area in developed economies and their particular significance to a country like Japan with a large aging population. Geriatrics & Gerontology International is now an international publication with contributions from around the world and published four times per year.
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