Nasopharyngeal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review.

IF 0.7 Q4 ONCOLOGY
Case Reports in Oncology Pub Date : 2024-12-05 eCollection Date: 2024-01-01 DOI:10.1159/000539018
Chiara Conti, Sabrina Nucera, Giuseppe Di Grazia, Federica Martorana, Fabio Motta, Paolo Vigneri, Alfio M Di Grazia
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引用次数: 0

Abstract

Introduction: Managing uncommon metastatic sites from different solid tumors is challenging since no available guidelines define the best therapeutic approaches for these rare clinical events. Thus, malignancies giving rise to distant metastases involving infrequent anatomical regions are often associated with a poor prognosis.

Case presentation: We present the case of a 75-year-old man who developed uncontrolled epistaxis following the detection of a metachronous nasopharyngeal metastasis from a previous lung adenocarcinoma. The lesion was identified with a computed tomography scan and its origin from the earlier non-small cell lung cancer was confirmed by a biopsy. The patient was successfully treated with radiation therapy and is currently continuing his oncological follow-up. To the best of our knowledge, this is the fifth reported case of a lung malignancy spreading to the nasopharyngeal region.

Conclusion: Meticulous patient monitoring and accurate radiological diagnosis followed by histological confirmation are of paramount importance for the management of uncommon metastatic sites. Likewise, a multidisciplinary approach is essential to devise the appropriate treatment strategy for each patient with locoregional interventions, such as radiation therapy, often playing a pivotal role for the management of symptomatic lesions in unusual anatomical sites.

肺腺癌鼻咽转移一例报告及文献复习。
导论:管理来自不同实体瘤的罕见转移部位是具有挑战性的,因为没有可用的指南定义这些罕见临床事件的最佳治疗方法。因此,恶性肿瘤引起的远端转移涉及罕见的解剖区域,往往与预后不良有关。病例介绍:我们提出的情况下,75岁的男子谁发展不受控制的鼻出血后检测到异时性鼻咽癌转移从以前的肺腺癌。病变由计算机断层扫描确定,其起源于早期的非小细胞肺癌,经活检证实。该患者已成功接受放射治疗,目前正在继续进行肿瘤随访。据我们所知,这是第5例报告的肺部恶性肿瘤扩散到鼻咽区。结论:细致的患者监测和准确的影像学诊断以及组织学证实对治疗罕见转移部位至关重要。同样,多学科方法对于为每个患者设计适当的局部区域干预治疗策略至关重要,例如放射治疗,通常在异常解剖部位的症状性病变管理中起关键作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
151
审稿时长
7 weeks
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