Liquid Crystal Elastomer for Compression Therapy

IF 10 2区 医学 Q1 ENGINEERING, BIOMEDICAL
Gaoweiang Dong, Fangchen Zhao, Zongyu Gao, Shengqiang Cai
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Abstract

Compression therapy is a widely used treatment for various disorders including venous leg ulcers. Traditional methods such as inelastic bandages and elastic stockings, have limitations in maintaining optimal pressure over time. Dynamic therapy devices offer intermittent pressure cycles but are often bulky or rigid. Here liquid crystal elastomer (LCE) is proposed for both static and dynamic compression therapy. Due to the soft elasticity of polydomain LCE, LCE-based static stocking can maintain consistent pressure over a wide range of leg diameters, permitting the tolerance of stocking application inconsistencies, various limb sizes, and interfacial pressure drop due to leg deswelling. The LCE-based dynamic stocking consists of monodomain LCEs with reversible thermal actuation, heating elements, and electronics. The dynamic stocking generates intermittent pressure from 20 to 60 mmHg with a slight temperature increase above 33 °C and offers pressure profile programmability. Furthermore, an untethered LCE-based dynamic compression device on a human leg is demonstrated. Both LCE-based static and dynamic stockings show minimal stress relaxation and reusability over 1000 cycles, ensuring long-term use in compression therapy applications.

Abstract Image

液晶弹性体用于压缩治疗。
压迫疗法是一种广泛应用于各种疾病的治疗方法,包括下肢静脉性溃疡。传统的方法,如无弹性绷带和弹性长袜,随着时间的推移,在保持最佳压力方面有局限性。动态治疗装置提供间歇性压力循环,但通常体积庞大或僵硬。本文提出了液晶弹性体(LCE)用于静态和动态压缩治疗。由于多域LCE的软弹性,基于LCE的静态袜子可以在很宽的腿径范围内保持一致的压力,允许容忍袜子应用不一致、不同的肢体尺寸以及由于腿肿胀引起的界面压力下降。基于lce的动态库存由可逆热致动的单域lce、加热元件和电子元件组成。动态储液可产生20 ~ 60 mmHg的间歇压力,温度在33℃以上略有升高,并具有压力剖面可编程性。此外,还演示了一种基于lce的无系绳动态压缩装置。基于lce的静态和动态长袜都显示出最小的应力松弛和超过1000次循环的可重复使用性,确保在压缩治疗应用中长期使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Advanced Healthcare Materials
Advanced Healthcare Materials 工程技术-生物材料
CiteScore
14.40
自引率
3.00%
发文量
600
审稿时长
1.8 months
期刊介绍: Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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