Revolutionizing X-ray Imaging: A Leap toward Ultra-Low-Dose Detection with a Cascade-Engineered Approach.

IF 12.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
ACS Central Science Pub Date : 2024-11-13 eCollection Date: 2024-11-27 DOI:10.1021/acscentsci.4c01296
Xin Song, Xinyuan Zhang, Tengyue He, Jiayi Wang, Hongwei Zhu, Renqian Zhou, Taimoor Ahmad, Osman M Bakr, Omar F Mohammed
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引用次数: 0

Abstract

X-ray detection technology is essential in various fields, including medical imaging and security checks. However, exposure to large doses of X-rays poses considerable health risks. Therefore, it is crucial to reduce the radiation dosage without compromising detection efficiency. To address this concern, we propose an innovative cascade-engineered approach that uses two interconnected single-crystal devices to mitigate dark current and enhance the detection limit. Using laboratory-grown methylammonium lead bromide (MAPbBr3) perovskite single crystals, we engineered devices that significantly reduced detection thresholds and improved signal-to-noise ratios (SNRs). The detection threshold dropped from 590 nGy·s-1 with the conventional method to 100 nGy·s-1 using the cascade approach, surpassing the most recent record of 500 nGy·s-1 achieved for MAPbBr3 devices under nearly identical conditions. The dark current was halved compared to that of conventional devices, and spatial resolution improved from 5.6 to 8.5 lp·mm-1. Imaging trials confirmed improved resolution and effectiveness at low doses, highlighting the approach's potential for medical diagnostics that prioritizes reducing radiation exposure without compromising image quality. The groundbreaking nature of this approach is highlighted by its adaptability across diverse electrical environments and crystal types, as evident in CdTe crystals, indicating its potential for widespread utilization in low-dose leakage monitoring and commercial X-ray devices.

革命性的x射线成像:用级联工程方法实现超低剂量检测的飞跃。
x射线探测技术在医学成像和安全检查等各个领域都是必不可少的。然而,暴露于大剂量的x射线会造成相当大的健康风险。因此,在不影响检测效率的前提下降低辐射剂量至关重要。为了解决这一问题,我们提出了一种创新的级联工程方法,该方法使用两个互连的单晶器件来减轻暗电流并提高检测极限。利用实验室培养的甲基溴化铅(MAPbBr3)钙钛矿单晶,我们设计的器件显著降低了检测阈值,提高了信噪比(SNRs)。检测阈值从传统方法的590 nGy·s-1下降到使用级联方法的100 nGy·s-1,超过了MAPbBr3器件在几乎相同条件下获得的500 nGy·s-1的最新记录。与传统器件相比,暗电流减少了一半,空间分辨率从5.6提高到8.5 lp·mm-1。成像试验证实了低剂量下分辨率和有效性的提高,突出了该方法在医疗诊断方面的潜力,即在不影响图像质量的情况下优先减少辐射暴露。这种方法的突破性本质在于其在不同电气环境和晶体类型中的适应性,如CdTe晶体所示,表明其在低剂量泄漏监测和商用x射线设备中的广泛应用潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Central Science
ACS Central Science Chemical Engineering-General Chemical Engineering
CiteScore
25.50
自引率
0.50%
发文量
194
审稿时长
10 weeks
期刊介绍: ACS Central Science publishes significant primary reports on research in chemistry and allied fields where chemical approaches are pivotal. As the first fully open-access journal by the American Chemical Society, it covers compelling and important contributions to the broad chemistry and scientific community. "Central science," a term popularized nearly 40 years ago, emphasizes chemistry's central role in connecting physical and life sciences, and fundamental sciences with applied disciplines like medicine and engineering. The journal focuses on exceptional quality articles, addressing advances in fundamental chemistry and interdisciplinary research.
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