The first example of a ring closing metathesis in a series of anthracycline antibiotics

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2024-12-06 DOI:10.1007/s11172-024-4430-4

A. A. Moiseeva, O. I. Artyushin

引用次数: 0

Abstract

A ring-closing metathesis giving 3-pyrroline ring in a series of anthracycline antibiotics on the example of N,N-diallyl derivative of daunorubicin using the first and the second generation Grubbs catalysts was reported. The suggested approach can be used to synthesize new anthracycline anticancer agents.

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这是一系列蒽环类抗生素中环闭合复分解的第一个例子

以柔红霉素N，N-二烯丙基衍生物为例，采用第一代和第二代Grubbs催化剂，在一系列蒽环类抗生素中合成了3-吡咯环。该方法可用于合成新的蒽环类抗癌药物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.