Adhesive joints are extensive used in various industrial applications. Bonded quality is crucial for ensuring structural integrity and safety. In this study, the nonlinear non-collinear wave mixing techniques were developed to nondestructive evaluate micro imperfections in adhesive joints, including adhesive degradation and bond weakening. Two testing schemes were proposed via the resonance conditions of the adhesive and substrate respectively, following the classical nonlinearity theories. Numerical simulations and experiments of non-collinear wave mixing were conducted to explore the feasibility of the proposed testing schemes for accessing two typical micro imperfections in adhesive joints. Both the simulation and experimental results demonstrate that the proposed nonlinear non-collinear wave mixing method is effective for nondestructive evaluation of the micro imperfections in adhesive joints. Moreover, the scheme via resonance conditions of adhesive exhibits a higher sensitive to the adhesive degradation, whereas the one relying on the resonance conditions of substrate exhibits a higher sensitive to bond weakening.