Advancements in radiobiology techniques and applications for personalized radiation therapy in nuclear medicine

IF 1.5 3区化学 Q3 CHEMISTRY, ANALYTICAL

Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2024-10-19 DOI:10.1007/s10967-024-09804-z

Yibo He, Maher Ali Rusho, Soumya V. Menon, Mandeep Kaur, Majid S. Jabir, Sabrean Farhan Jawad, Thikra F. Hasan, Mazin A. A. Najm, Mohammed Abed Jawad, Ali J. Khelief

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Abstract

Personalized radiation therapy in Nuclear Medicine aims to tailor treatment regimens to individual patients based on their unique biological characteristics. Recent advancements in radiobiology techniques offer promising avenues for achieving this goal. This review explores key developments in radiobiology, including molecular imaging, radiomics, biomarkers of radiosensitivity, microdosimetry, theranostics, and artificial intelligence. These techniques enable a more precise understanding of tumor biology, prediction of treatment response, and optimization of radiation dose delivery. By integrating radiobiological information into clinical decision-making, personalized radiation therapy in Nuclear Medicine can lead to improved treatment outcomes and reduced side effects.

Graphical abstract

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核医学个体化放射治疗的放射生物学技术与应用进展

核医学中的个体化放射治疗旨在根据患者独特的生物学特征为其量身定制治疗方案。放射生物学技术的最新进展为实现这一目标提供了有希望的途径。这篇综述探讨了放射生物学的主要发展，包括分子成像、放射组学、放射敏感性生物标志物、微剂量学、治疗学和人工智能。这些技术能够更精确地了解肿瘤生物学，预测治疗反应，并优化辐射剂量的传递。通过将放射生物学信息整合到临床决策中，核医学中的个性化放射治疗可以改善治疗效果并减少副作用。图形抽象

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来源期刊

Journal of Radioanalytical and Nuclear Chemistry 化学-分析化学

CiteScore

2.80

自引率

18.80%

发文量

504

审稿时长

2.2 months

期刊介绍： An international periodical publishing original papers, letters, review papers and short communications on nuclear chemistry. The subjects covered include: Nuclear chemistry, Radiochemistry, Radiation chemistry, Radiobiological chemistry, Environmental radiochemistry, Production and control of radioisotopes and labelled compounds, Nuclear power plant chemistry, Nuclear fuel chemistry, Radioanalytical chemistry, Radiation detection and measurement, Nuclear instrumentation and automation, etc.