Survey on Alopecia Areata Patients' Reported Factors that Determine Severity of Alopecia Areata: A Nationwide Multicenter Study.

Jung Eun Kim, Subin Lee, Hoon Kang, Young Lee, Do-Young Kim, Hyunsun Park, Hyun-Tae Shin, Yong Hyun Jang, Kihyuk Shin, Ji Hae Lee, Jee Woong Choi, Byung Choel Park, Beom Joon Kim, Soo Hong Seo, Chong Hyun Won, Jin Park, Min Sung Kim, Sang Seok Kim, Bark-Lynn Lew, Chang-Hun Huh, Ohsang Kwon, Yang Won Lee, Moon-Bum Kim
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Abstract

Background: Alopecia areata (AA) is characterized by hair loss on the scalp and body, significantly impacting patients' quality of life based on its severity.

Objective: This study aims to identify crucial factors influencing the perception of severe AA from the patients' viewpoint.

Methods: A web-based survey was conducted among AA patients attending dermatology departments at 21 university hospitals in Korea. The survey comprised 17 criteria, exploring both clinical characteristics of AA patients and subjective determinants of disease severity.

Results: A total of 791 AA patients and their caregivers participated in the survey. Approximately 30% of respondents developed AA during childhood, with 43.5% experiencing chronic courses lasting over 3 years. Half of the participants exhibited more than 20% scalp hair loss, and 42% reported additional hair loss on other body parts, such as eyelashes and nose hair. Most respondents agreed that patients with ≥20% scalp hair loss should be categorized as having severe AA. They also identified longer disease duration, involvement of non-scalp body hair, treatment refractoriness, and social or mental impairment requiring medical intervention as factors indicating increased disease severity.

Conclusion: This survey underscores the significant impact of AA on patients' quality of life and highlights existing unmet needs in current treatment modalities.

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