Is Fetal Reduction Necessary in Triplet Pregnancy? Single Tertiary Center Experience.

IF 0.7 4区医学 Q4 PATHOLOGY

Fetal and Pediatric Pathology Pub Date : 2025-01-01 Epub Date: 2024-12-03 DOI:10.1080/15513815.2024.2434050

Sukran Dogru, Huriye Ezveci, Fikriye Karanfil Yaman, Fatih Akkus, Pelin Bahceci, Ali Acar

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引用次数: 0

Abstract

Objective: This study aims to evaluate the perinatal outcomes of triplet pregnancies reduced from triplets to twins with fetal reduction (FR), followed expectantly without FR, and reduced to triplets from higher-order multiple pregnancies (HOMP) with FR.

Materials and methods: Multifetal pregnancies followed at the university hospital in the last 8 years were evaluated retrospectively. The study group was composed of three groups. The first group was those who started as trichorionic-triamniotic (TCTA) triplets and were followed by triplets. The second group consisted of HOMPs reduced to TCTA triplets with FR. The third group consisted of pregnant women who started as TCTA triplets and were reduced to dichorionic-diamniotic (DCDA) twins with FR.

Results: A total of 69 multifetal pregnancies were included in the study. No statistical difference was observed between miscarriage rates in all groups (p = 0.190). Birth rates below 32 weeks were similar between groups (p = 0.158). The birth rates below 34 weeks were statistically significantly lower in the group in which DCDA was reduced by TCTA compared to the other two groups (p = 0.001). The first and second fetus weights in the group reduced to DCDA twins from TCTA were higher than the group followed expectantly, they were similar to the triplets reduced from HOMP. Stillbirth rates were similar in all groups (p = 0.057).

Conclusion: In TCTA pregnancies, when the priority is three live-born babies, expectant management seems to be a reasonable choice, considering the low rate of miscarriage and high rate of survivor neonates in this group.

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三胞胎妊娠有必要减少胎儿数量吗？单一三级中心体验。

目的：探讨三胞胎妊娠从三胞胎降为双胎并胎儿减少（FR）、未发生胎儿减少（FR）、高序多胎妊娠降为三胞胎合并胎儿减少（FR）的围产儿结局。材料和方法：回顾性分析大学附属医院近8年的多胎妊娠。研究小组由三组组成。第一组是三绒毛膜-三羊膜（TCTA）三胞胎，随后是三胞胎。第二组为经TCTA治疗后的三胞胎，第三组为经TCTA治疗后的双绒毛膜-双羊膜（DCDA）双胞胎。结果：本研究共纳入69例多胎妊娠。各组流产率差异无统计学意义（p = 0.190）。32周以下的出生率组间相似（p = 0.158）。与其他两组相比，TCTA减少DCDA组34周以下的出生率有统计学意义显著降低（p = 0.001）。TCTA降为DCDA双胞胎组的第一胎和第二胎体重高于预期组，与HOMP降为三胞胎相似。各组死胎率相似（p = 0.057）。结论：在TCTA妊娠中，当优先考虑三个活产婴儿时，考虑到该组低流产率和高存活率，准产管理似乎是一种合理的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Fetal and Pediatric Pathology 医学-病理学

CiteScore

3.00

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Fetal and Pediatric Pathology is an established bimonthly international journal that publishes data on diseases of the developing embryo, newborns, children, and adolescents. The journal publishes original and review articles and reportable case reports. The expanded scope of the journal encompasses molecular basis of genetic disorders; molecular basis of diseases that lead to implantation failures; molecular basis of abnormal placentation; placentology and molecular basis of habitual abortion; intrauterine development and molecular basis of embryonic death; pathogenisis and etiologic factors involved in sudden infant death syndrome; the underlying molecular basis, and pathogenesis of diseases that lead to morbidity and mortality in newborns; prenatal, perinatal, and pediatric diseases and molecular basis of diseases of childhood including solid tumors and tumors of the hematopoietic system; and experimental and molecular pathology.