Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial.

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-03 DOI:10.1007/s41999-024-01100-z

Anna Schubert, Thea Laurentius, Svenja Lange, Jens Bertram, Leo Cornelius Bollheimer, Marcel Schweiker, Rania Christoforou

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引用次数: 0

Abstract

Purpose: During hospitalization, circadian rhythms and sleep are often disrupted, which has negative effects on health outcomes. Therefore, we aimed to investigate whether a daylight intervention in the morning could improve the circadian rhythms of cortisol and melatonin and enhance objective and subjective sleep quality in geriatric patients.

Methods: The present study is a randomized, two-period crossover trial conducted in a geriatric ward in 15 non-demented geriatric trauma patients with a mean age of 83.1 ± 5.4 years. All patients underwent a daylight intervention period, during which they were exposed to a daylight lamp from 8:00 to 13:00 h, and a control period of 6 days each. Cortisol and melatonin levels were measured on day 5 of each period. Objective and subjective sleep quality were assessed using actigraphy and questionnaires, respectively. Within-participant differences between periods were investigated for all parameters.

Results: A trend towards improvement in cortisol and melatonin rhythmicity was found. An increase in mean melatonin levels from 0.3 ± 0.1 to 0.9 ± 0.8 ng/L was observed during the intervention period (p = .063). There was also a trend towards increased sleep efficiency, whereas subjective sleep quality tended to decrease. None of the results were significant.

Conclusion: A daylight intervention in the morning led to a positive trend in cortisol and melatonin rhythmicity, whereas no improvement in subjective sleep quality was found.

Trial registration: DRKS00028626 at German Clinical Trials Register, 13.06.2022.

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早晨日光干预对老年患者昼夜节律和睡眠的影响：一项随机交叉试验

目的：在住院期间，昼夜节律和睡眠经常被打乱，这对健康结果有负面影响。因此，我们的目的是研究早晨日光干预是否可以改善老年患者皮质醇和褪黑激素的昼夜节律，提高客观和主观睡眠质量。方法：本研究是一项随机，两期交叉试验，在老年病房进行15例平均年龄为83.1±5.4岁的非痴呆性老年创伤患者。所有患者均进入日光干预期，干预期为8:00 ~ 13:00 h日光照射，对照组为6 d。在每个周期的第5天测量皮质醇和褪黑激素水平。客观和主观睡眠质量分别采用活动记录仪和问卷调查进行评估。研究了所有参数在不同时期参与者内部的差异。结果：发现皮质醇和褪黑素节律性有改善的趋势。在干预期间，平均褪黑激素水平从0.3±0.1增加到0.9±0.8 ng/L （p = 0.063）。睡眠效率也有提高的趋势，而主观睡眠质量却有下降的趋势。没有一个结果是显著的。结论：早晨日光干预导致皮质醇和褪黑激素节律性呈阳性趋势，而主观睡眠质量没有改善。试验注册：DRKS00028626在德国临床试验注册，13.06.2022。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Geriatric Medicine GERIATRICS & GERONTOLOGY-

CiteScore

6.70

自引率

2.60%

发文量

114

审稿时长

6-12 weeks

期刊介绍： European Geriatric Medicine is the official journal of the European Geriatric Medicine Society (EUGMS). Launched in 2010, this journal aims to publish the highest quality material, both scientific and clinical, on all aspects of Geriatric Medicine. The EUGMS is interested in the promotion of Geriatric Medicine in any setting (acute or subacute care, rehabilitation, nursing homes, primary care, fall clinics, ambulatory assessment, dementia clinics..), and also in functionality in old age, comprehensive geriatric assessment, geriatric syndromes, geriatric education, old age psychiatry, models of geriatric care in health services, and quality assurance.