Pediatric Uveitis in a Tertiary Referral Center in East China: Clinical Patterns and Visual Outcomes.

IF 1.8 4区 医学 Q3 OPHTHALMOLOGY
Journal of Ophthalmology Pub Date : 2024-11-21 eCollection Date: 2024-01-01 DOI:10.1155/joph/5015614
Boya Lei, Xianjin Zhou, Ruiping Gu, Qinmeng Shu, Xinyi Ding, Rui Jiang, Qing Chang, Gezhi Xu, Haimei Liu, Li Sun, Min Zhou
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引用次数: 0

Abstract

Background: To describe the clinical patterns and visual outcomes of pediatric uveitis at a tertiary referral center in East China. Methods: Retrospective case series. Clinical records of patients with pediatric uveitis who presented between January 2014 and July 2021 were reviewed. Results: The children included (n = 283; 146 females, 137 males) had a mean age at presentation of 10.6 ± 3.5 years. There was a predominance of chronic (62.9%), noninfectious (81.3%) disease, and anterior uveitis was the most common uveitis type (54.8%). Idiopathic chronic anterior uveitis (17.3%) and juvenile idiopathic arthritis (JIA)-associated anterior uveitis (16.3%) were the most common noninfectious types; ocular toxocariasis (14.8%) and viral retinitis (1.4%) were the most common infectious etiologies. Ocular complications were observed in 53.0% of patients during follow-up. Systemic immunosuppressive therapy was administered to 66.8% of patients, 67.2% of whom required immunosuppressive drugs and/or biological agents (127/189 children). Surgical treatment was conducted in 38 (13.4%) patients. Improvement or preservation of visual acuity was observed in 95.2% of patients for whom follow-up visual acuity was recorded (179/188 patients). Conclusions: Pediatric uveitis was predominantly chronic and noninfectious, with anterior involvement. Systemic therapy was required by most patients, and most eyes showed improved visual acuity.

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来源期刊
Journal of Ophthalmology
Journal of Ophthalmology MEDICINE, RESEARCH & EXPERIMENTAL-OPHTHALMOLOGY
CiteScore
4.30
自引率
5.30%
发文量
194
审稿时长
6-12 weeks
期刊介绍: Journal of Ophthalmology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the anatomy, physiology and diseases of the eye. Submissions should focus on new diagnostic and surgical techniques, instrument and therapy updates, as well as clinical trials and research findings.
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