Design Strategies and Application Potential of Multifunctional Hydrogels for Promoting Angiogenesis.

IF 6.6 2区医学 Q1 NANOSCIENCE & NANOTECHNOLOGY

International Journal of Nanomedicine Pub Date : 2024-11-27 eCollection Date: 2024-01-01 DOI:10.2147/IJN.S495971

Menglei Wang, Jiawen Chen, Yawen Luo, Meixin Feng, Qianwen Yang, Yingmei Tang, Ziyi Tang, Wantong Xiao, Yue Zheng, Li Li

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引用次数: 0

Abstract

Hydrogels can be rationally designed as multifunctional platforms with structures and functions for various biomedical applications. Because of their excellent biochemical and mechanical properties, hydrogels have shown great potential for promoting angiogenesis, and an increasing amount of research has been devoted to designing and developing new hydrogels. However, a systematic and detailed review of hydrogels that promote angiogenesis is lacking. This paper comprehensively summarizes the design strategies of different kinds of functional hydrogels that promote angiogenesis, with anti-oxidant, substance-delivery, stimulus-responsive, self-healing, conductive, and wound-monitoring properties. The applications of hydrogels in wound healing, bone regeneration, and treatment of myocardial ischemia are discussed. Finally, future development directions of functional hydrogels promoting angiogenesis are proposed along with new strategies for the treatment of related diseases.

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来源期刊

International Journal of Nanomedicine NANOSCIENCE & NANOTECHNOLOGY-PHARMACOLOGY & PHARMACY

CiteScore

14.40

自引率

3.80%

发文量

511

审稿时长

1.4 months

期刊介绍： The International Journal of Nanomedicine is a globally recognized journal that focuses on the applications of nanotechnology in the biomedical field. It is a peer-reviewed and open-access publication that covers diverse aspects of this rapidly evolving research area. With its strong emphasis on the clinical potential of nanoparticles in disease diagnostics, prevention, and treatment, the journal aims to showcase cutting-edge research and development in the field. Starting from now, the International Journal of Nanomedicine will not accept meta-analyses for publication.