Structure Confirmation of Three New Psychoactive Substances and Qualitative Identification of Unknown Substances.

Q3 Medicine

法医学杂志 Pub Date : 2024-08-25 DOI:10.12116/j.issn.1004-5619.2023.330101

Zong-Yang Nie, Wei Hu, Ling-Yu Li, Qing-Bo Zhang, Xin Huang, Bo Li

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引用次数: 0

Abstract

Objectives: To establish the structural confirmation methods of three suspected new psychoactive substances (NPSs), and explore a more general qualitative testing method.

Methods: Infrared absorption spectroscopy (IR), gas chromatography-mass spectrometry (GC-MS), ¹H-nuclear magnetic resonance spectroscopy (¹H-NMR), ¹³C-nuclear magnetic resonance spectroscopy (¹³C-NMR), ¹⁹F-nuclear magnetic resonance spectroscopy (¹⁹F-NMR) and other techniques were used to identify the composition and structure of 5 samples containing suspected NPS submitted by public security bureaus.

Results: NPSs were found in the above 5 samples, and 3 were confirmed as NPS included in the newly listed controlled substances on July 1, 2024, namely 2-(methylamino)-2-(2-methylphenyl)cyclohexan-1-one (2-MDCK), 2-(ethylamino)-2-(2-fluorophenyl)cyclohexan-l-one (2-FXE), 1-(3,4-methylenedioxyphenyl)-2-(dimethylamino)pentan-1-one (dipentylone), respectively. The first two substances were phencyclidine NPS, and the third substance was synthetic cathinone NPS.

Conclusions: This study systematically summarizes the distinguishing features of the infrared absorption spectrometry, nuclear magnetic resonance spectroscopy and mass spectrometry of three NPSs, which can provide a reference for the qualitative identification of unknown substances.

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来源期刊

法医学杂志 Medicine-Pathology and Forensic Medicine

CiteScore

1.50

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0.00%

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