Cervical lymph node dissection fails to improve survival in T2N0M0 glottic squamous cell carcinoma: a large-scale real-world study.

IF 1.9 3区 医学 Q2 OTORHINOLARYNGOLOGY
Zhuqi Chen, Xinyu Zhang, Wenbin Lei, Lin Chen
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引用次数: 0

Abstract

Objective: This study aimed to evaluate the therapeutic efficacy of cervical lymph node dissection in patients with T2N0M0 glottic squamous cell carcinoma.

Methods: Among 260,068 head and neck cancer patients, 861 cases of T2N0M0 glottic squamous cell carcinoma were selected, of which 113 underwent selective lymph node dissection, and 748 did not receive dissection. The overall survival rates and disease-specific survival rates were compared between the two groups to assess efficacy.

Results: There was no significant difference in overall survival rates (median survival time of 57 months vs. 62 months, p = 0.34) and disease-specific survival rates (p = 0.79) between the two groups. Patients aged ≥ 60 years were at a higher risk, whereas neck dissection, gender, and degree of differentiation did not show significant risk differences in this study.

Conclusion: Cervical lymph node dissection in patients with T2N0 glottic squamous cell carcinoma did not demonstrate a significant advantage in survival rates.

颈部淋巴结清扫不能提高T2N0M0声门鳞状细胞癌患者的生存率:一项大规模的现实世界研究。
目的:探讨颈淋巴结清扫术治疗T2N0M0型声门鳞状细胞癌的疗效。方法:在260,068例头颈癌患者中,选择T2N0M0型声门鳞状细胞癌861例,其中113例行选择性淋巴结清扫,748例未行淋巴结清扫。比较两组患者的总生存率和疾病特异性生存率,以评估疗效。结果:两组患者的总生存率(中位生存时间57个月vs. 62个月,p = 0.34)和疾病特异性生存率(p = 0.79)无显著差异。≥60岁的患者风险较高,而本研究中颈部解剖、性别和分化程度无显著风险差异。结论:T2N0型声门鳞状细胞癌颈淋巴结清扫术在生存率上没有明显优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.30
自引率
7.70%
发文量
537
审稿时长
2-4 weeks
期刊介绍: Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.
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