Bilateral occlusive retinal vasculitis secondary to intravitreal faricimab injection: a case report and review of literature.

IF 4.1 1区 医学 Q1 OPHTHALMOLOGY
Yong Min Lee, Rajya Gurung, Jagjit Singh Gilhotra, Sumu Simon, Sudha Cugati
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引用次数: 0

Abstract

Background: This article describes a rare occurrence of bilateral retinal occlusive vasculitis secondary to intravitreal faricimab injection.

Case presentation: A 72-year-old female with age-related macular degeneration presented with bilateral retinal occlusive vasculitis following intravitreal faricimab injections. The patient was treated with 3 days of intravenous methylprednisolone followed by oral prednisolone taper and topical steroid therapy. Resolution of retinal occlusive vasculitis was observed 2 months post treatment.

Conclusions: Retinal occlusive vasculitis is a rare complication of intravitreal anti-vascular endothelial growth factor (anti-VEGF), particularly with faricimab injections. We also present a review of literature regarding retinal occlusive vasculitis following intravitreal anti-VEGF injections and propose further information regarding its pathophysiology.

法利西单抗玻璃体内注射继发于双侧视网膜闭塞性血管炎1例报告及文献复习。
背景:这篇文章描述了一例罕见的双侧视网膜血管闭塞性炎继发于玻璃体内注射法利西单抗。病例介绍:一名72岁女性老年性黄斑变性患者在玻璃体内注射法利西单抗后出现双侧视网膜闭塞性血管炎。患者接受3天静脉注射甲基强的松龙,随后口服强的松龙减量和局部类固醇治疗。治疗2个月后观察视网膜闭塞性血管炎的消退。结论:视网膜闭塞性血管炎是玻璃体内抗血管内皮生长因子(anti-VEGF)治疗的罕见并发症,尤其是法利西单抗注射。我们还回顾了关于玻璃体内注射抗vegf后视网膜闭塞性血管炎的文献,并提出了有关其病理生理学的进一步信息。
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来源期刊
Eye and Vision
Eye and Vision OPHTHALMOLOGY-
CiteScore
8.60
自引率
2.40%
发文量
89
审稿时长
15 weeks
期刊介绍: Eye and Vision is an open access, peer-reviewed journal for ophthalmologists and visual science specialists. It welcomes research articles, reviews, methodologies, commentaries, case reports, perspectives and short reports encompassing all aspects of eye and vision. Topics of interest include but are not limited to: current developments of theoretical, experimental and clinical investigations in ophthalmology, optometry and vision science which focus on novel and high-impact findings on central issues pertaining to biology, pathophysiology and etiology of eye diseases as well as advances in diagnostic techniques, surgical treatment, instrument updates, the latest drug findings, results of clinical trials and research findings. It aims to provide ophthalmologists and visual science specialists with the latest developments in theoretical, experimental and clinical investigations in eye and vision.
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