Macro-vacuolar steatosis in a cirrhotic liver mimicking metastatic disease

Q4 Medicine
Pietro Pitrone MD , Agatino Cacciola MD , Antonino Cattafi MD , Alessia Maria Romeo MD , Annalisa Cracò MD. , Francesco Marcello Aricò MD , Nicola Migliaccio MD , Francesca Magnani MD , Italo Giuseppe Bellone MD , Simona Caloggero MD , Giampiero Mastroeni MD
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引用次数: 0

Abstract

Multinodular steatosis represents a relatively uncommon manifestation of fatty liver disease (FLD). Co-morbidities such as metabolic syndrome or cirrhosis are often associated. Despite typical features of imaging (ultrasound, CT, and MRI), core biopsy sometimes remains the gold standard for diagnosis. We describe the case of a 57-year-old male patient with a long history of hepatic cirrhosis and a recent diagnosis of carcinoma of the tongue, successfully treated. Due to the occurrence of nausea, diarrhea and jaundice the patient is admitted to Our Hospital where ultrasound examination and contrast-enhanced CT are performed, showing global hypoechogenicity of the liver parenchyma with multiple hypo-attenuating lesions. To rule out metastatic lesions, contrast-enhanced CT of the thorax and cranium and gastroscopy and colonoscopy are performed, with no evidence of primary malignancy. Core biopsy reveals macro-vacuolar steatosis within a cirrhotic liver with regenerative aspects.
模拟转移性疾病的肝硬化大空泡性脂肪变性
多结节性脂肪变性是脂肪肝(FLD)的一种相对少见的表现。合并症,如代谢综合征或肝硬化往往是相关的。尽管有典型的影像学特征(超声、CT和MRI),核心活检有时仍然是诊断的金标准。我们描述的情况下,一个57岁的男性患者与长期的历史肝硬化和最近的舌癌诊断,成功治疗。患者因出现恶心、腹泻、黄疸入院,行超声及增强CT检查,发现肝实质整体低回声,多发低衰减病灶。为了排除转移性病变,我们进行了胸部和头盖骨对比增强CT,胃镜和结肠镜检查,未发现原发性恶性肿瘤的证据。核心活检显示肝硬化大空泡性脂肪变性伴再生。
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来源期刊
Radiology Case Reports
Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
1.10
自引率
0.00%
发文量
1074
审稿时长
30 days
期刊介绍: The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.
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