Rare occurrence of triple primary malignant tumors: Dermatofibrosarcoma protuberans, lung adenocarcinoma and papillary thyroid carcinoma in a patient with genetic evaluation

Q4 Medicine
Luan Minh Bao Tran , Minh Duc Do , Truong Hung Nguyen , Ngoc-Minh Vuong
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引用次数: 0

Abstract

Triple primary malignancies are rare, involving the occurrence of three distinct, unrelated cancers in a single patient, requiring a personalized, multidisciplinary treatment approach. A 69-year-old male was diagnosed with dermatofibrosarcoma protuberans (DFSP), lung adenocarcinoma, and papillary thyroid carcinoma. After amputation for DFSP, following staging and genetic evaluation, a multidisciplinary tumor board designed a tailored treatment plan, adjuvant chemotherapy for lung adenocarcinoma while monitor regularly the thyroid carcinoma via ultrasound. This case highlights the extreme rarity of this triple primary cancers combination and emphasizes the need for individualized treatment planning. Each cancer's unique characteristics, prognosis, and potential interactions must be considered, alongside the patient's overall health and treatment tolerability, to optimize outcomes in such complex cases.
三原发恶性肿瘤:隆突性皮肤纤维肉瘤、肺腺癌及甲状腺乳头状癌的罕见发生
三重原发性恶性肿瘤是罕见的,涉及三个不同的,不相关的癌症发生在一个病人,需要个性化的,多学科的治疗方法。一个69岁的男性被诊断为皮肤纤维肉瘤隆突(DFSP),肺腺癌和甲状腺乳头状癌。在DFSP截肢后,在进行分期和基因评估后,一个多学科肿瘤委员会为肺腺癌设计了量身定制的治疗方案,辅助化疗,同时定期通过超声监测甲状腺癌。该病例强调了这种三原发癌症合并的极端罕见性,并强调了个性化治疗计划的必要性。每种癌症的独特特征、预后和潜在的相互作用必须与患者的整体健康和治疗耐受性一起考虑,以优化此类复杂病例的结果。
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来源期刊
Radiology Case Reports
Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
1.10
自引率
0.00%
发文量
1074
审稿时长
30 days
期刊介绍: The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.
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