Risk Factors of Complications After Uterine Artery Embolisation for Symptomatic Fibroids: A Case–Control Study

IF 4.7 1区医学 Q1 OBSTETRICS & GYNECOLOGY

Bjog-An International Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 DOI:10.1111/1471-0528.18023

Adeline de Wit, Marc-Florent Tassi, Denis Herbreteau, Henri Marret

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引用次数: 0

Abstract

Objective

We aim to clarify potential risk factors of complications after uterine artery embolisation (UAE).

Setting

Complications after uterine artery embolisation (UAE) for symptomatic fibroids are rare, but failure of treatment occurs for approximately 13%–24% of patients at 10 years.

Design

We conducted a case–control study including all complications post UAE over 15 years in our specialised unit.

Population

All Grade 2 complications (or worse) for the Society of Interventional Radiology Standards of Practice Committee complications post UAE were considered. One thousand one hundred seventy-two UAE were performed.

Methods

Complications were divided into two groups: early (< 1 month) or late (≥ 1 month) to differentiate complications from failure of procedure. Multinomial analysis was conducted to assess links between complications and potential risk factors.

Results

Sixty-nine (0.06%) complications were found: 24.6% hospitalisation for pain (n = 17/69), 30.4% for infection (n = 21/69) and 2.9% expulsion of fibroid (n = 2/69). Overall, 31 patients underwent a second procedure (45%).

Main Outcome Measures

Intra-uterine device and multiple fibroids were strongly related to early complications (OR_early = 4.44, IC 95%: 1.5–13.3 and OR_early = 3.7, IC 95%: 1.2–11.3, respectively). The only factor that appeared to be associated with risk of early and late complications was the major fibroid's diameter (for an increased size of 25 mm, OR_early = 1.7, IC 95%: 1.1–2.6; OR_late = 1.5, IC 95%: 1.04–2.2).

Conclusion

Our study enlightens about the potential risk factors of UAE's complications and differentiate their impact between early and late complications.

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症状性肌瘤子宫动脉栓塞术后并发症的危险因素：一项病例对照研究

我们的目的是澄清子宫动脉栓塞（UAE）后并发症的潜在危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bjog-An International Journal of Obstetrics and Gynaecology 医学-妇产科学

CiteScore

10.90

自引率

5.20%

发文量

345

审稿时长

3-6 weeks

期刊介绍： BJOG is an editorially independent publication owned by the Royal College of Obstetricians and Gynaecologists (RCOG). The Journal publishes original, peer-reviewed work in all areas of obstetrics and gynaecology, including contraception, urogynaecology, fertility, oncology and clinical practice. Its aim is to publish the highest quality medical research in women''s health, worldwide.