A comprehensive review on niclosamide detection in foodstuffs and pharmaceutical preparations: Diverse analytical approaches and emerging techniques

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal Pub Date : 2024-11-29 DOI:10.1016/j.microc.2024.112284

Kalyani A. Birari , Pravin O. Patil , Shadma Wahab , Mohammad Khalid , Mahendra Mahajan , Rahul S. Tade , Sanjaykumar B. Bari , Zamir G. Khan

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Abstract

Niclosamide (NIC), a widely recognized antiparasitic and anthelmintic agent, plays a critical role in aquaculture and livestock breeding, particularly in controlling parasitic growth and schistosomiasis, endorsed by the WHO as an essential molluscicide. However, excessive use has led to NIC residues in animal products and environmental sources, posing significant health risks. The detection of NIC residues in food products has thus become essential to safeguarding public health. This review provides a detailed overview of NIC regulatory residue limits and the associated health risks of NIC residue in food sources. In addition, it delves into various established detection methods, critically evaluating their strengths and limitations. The evaluation seeks to improve food product safety and monitoring by emphasising important methodologies and suggesting improvements in detection efficiency and accuracy. Lastly, future perspectives for the advancement of sophisticated analytical techniques are examined, providing information on how NIC detection techniques may change in response to escalating safety requirements.

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来源期刊

Microchemical Journal 化学-分析化学

CiteScore

8.70

自引率

8.30%

发文量

1131

审稿时长

1.9 months

期刊介绍： The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field. Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.