Iliac branch endoprosthesis for endovascular treatment of complex aorto-iliac aneurysms - from device design to practical experience: how to translate physiology considerations into clinical applications.

IF 2.6 4区 医学 Q2 PHYSIOLOGY
Apostolos G Pitoulias, Mario D Oria, Konstantinos P Donas, Matti Jubouri, Damian M Bailey, Ian M Williams, Mohamad Bashir
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Abstract

This article provides a narrative review of the current literature and our expert opinion concerning the iliac branch endoprosthesis (IBE) and its use in the treatment of complex abdominal aortic aneurysm (AAA) cases with concomitant aneurysmal involvement of the common iliac artery (CIA) and/or the internal iliac artery (IIA). Up to 25% of those with an AAA may present with extension of the aneurysmal disease into the iliac vessels. This anatomy may complicate the standard endovascular aortic repair (EVAR) procedure, as the available length of distal landing zones is altered. The optimum treatment requires both the adequate sealing of the distal landing zone as well as the preservation of the pelvic circulation through the IIA. Extensive preoperative assessment of the anatomy, as well as an accurate deployment following all procedural steps, enables endovascular treatment of complex aorto-iliac aneurysms safe with excellent midterm clinical outcomes. The current literature shows that the utilization of the IBE offers a durable treatment of these complicated cases with results equal to those of the open repair, without the associated morbidity. Preservation of the pelvic circulation is recommended to prevent pelvic ischaemic symptoms and can also be carried out on both sides provided certain anatomical requirements are met.

髂分支假体用于血管内治疗复杂的主动脉-髂动脉瘤——从装置设计到实践经验:如何将生理考虑转化为临床应用。
本文对髂分支内假体(IBE)及其在复杂腹主动脉瘤(AAA)合并髂总动脉(CIA)和/或髂内动脉(IIA)的治疗中的应用进行了综述和我们的专家意见。高达25%的AAA患者可能表现为动脉瘤疾病延伸至髂血管。这种解剖结构可能使标准的血管内主动脉修复(EVAR)手术复杂化,因为远端着陆区的可用长度发生了改变。最佳的治疗方法既需要对远端着落区进行充分的密封,也需要通过IIA保留骨盆循环。广泛的术前解剖评估,以及在所有程序步骤下的准确部署,使得血管内治疗复杂的主动脉-髂动脉瘤安全且具有良好的中期临床结果。目前的文献表明,利用IBE为这些复杂的病例提供了持久的治疗,其结果与开放修复相同,没有相关的发病率。建议保留盆腔循环以防止盆腔缺血症状,也可以在满足一定解剖要求的情况下在两侧进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Experimental Physiology
Experimental Physiology 医学-生理学
CiteScore
5.10
自引率
3.70%
发文量
262
审稿时长
1 months
期刊介绍: Experimental Physiology publishes research papers that report novel insights into homeostatic and adaptive responses in health, as well as those that further our understanding of pathophysiological mechanisms in disease. We encourage papers that embrace the journal’s orientation of translation and integration, including studies of the adaptive responses to exercise, acute and chronic environmental stressors, growth and aging, and diseases where integrative homeostatic mechanisms play a key role in the response to and evolution of the disease process. Examples of such diseases include hypertension, heart failure, hypoxic lung disease, endocrine and neurological disorders. We are also keen to publish research that has a translational aspect or clinical application. Comparative physiology work that can be applied to aid the understanding human physiology is also encouraged. Manuscripts that report the use of bioinformatic, genomic, molecular, proteomic and cellular techniques to provide novel insights into integrative physiological and pathophysiological mechanisms are welcomed.
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