A novel BODIPY-derived colorimetric and ratiometric dual-mode fluorescent probe for highly sensitive and visual detection of sulfite in food and living organisms.

IF 3.8 2区 化学 Q1 BIOCHEMICAL RESEARCH METHODS
Chunjie Zhang, Yueyin Liang, Shuai Gong, Zhiyuan Meng, Zhonglong Wang, Shifa Wang
{"title":"A novel BODIPY-derived colorimetric and ratiometric dual-mode fluorescent probe for highly sensitive and visual detection of sulfite in food and living organisms.","authors":"Chunjie Zhang, Yueyin Liang, Shuai Gong, Zhiyuan Meng, Zhonglong Wang, Shifa Wang","doi":"10.1007/s00216-024-05658-2","DOIUrl":null,"url":null,"abstract":"<p><p>Sulfite, widely used as a food additive, performs indispensable functions in the field of food sterilization, bleaching, and antisepsis. However, the overuse of sulfite may destroy food nutrition and pose health risks to people. In this work, an innovative BODIPY-based fluorescent probe (BODIPY-DBC) was constructed for highly sensitive recognition of sulfite. The BODIPY-DBC probe possessed both colorimetric and ratiometric dual mode, a low detection limit (33.12 nM), high sensitivity, a wide pH usage range (5-12), a fast response time (2 min), and superior fluorescence imaging capability for detecting sulfite. The recognition mechanism was certificated by <sup>1</sup>H NMR titration, HRMS analysis, and DFT calculation. The BODIPY-DBC probe was not only loaded on test strips for detecting sulfite conveniently with the naked eye, but also employed to detect sulfite content in real food samples to ensure food safety. Furthermore, it also achieved excellent performances for monitoring sulfite in dual-channel fluorescence imaging (HeLa cell and zebrafish).</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical and Bioanalytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s00216-024-05658-2","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0

Abstract

Sulfite, widely used as a food additive, performs indispensable functions in the field of food sterilization, bleaching, and antisepsis. However, the overuse of sulfite may destroy food nutrition and pose health risks to people. In this work, an innovative BODIPY-based fluorescent probe (BODIPY-DBC) was constructed for highly sensitive recognition of sulfite. The BODIPY-DBC probe possessed both colorimetric and ratiometric dual mode, a low detection limit (33.12 nM), high sensitivity, a wide pH usage range (5-12), a fast response time (2 min), and superior fluorescence imaging capability for detecting sulfite. The recognition mechanism was certificated by 1H NMR titration, HRMS analysis, and DFT calculation. The BODIPY-DBC probe was not only loaded on test strips for detecting sulfite conveniently with the naked eye, but also employed to detect sulfite content in real food samples to ensure food safety. Furthermore, it also achieved excellent performances for monitoring sulfite in dual-channel fluorescence imaging (HeLa cell and zebrafish).

求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
8.00
自引率
4.70%
发文量
638
审稿时长
2.1 months
期刊介绍: Analytical and Bioanalytical Chemistry’s mission is the rapid publication of excellent and high-impact research articles on fundamental and applied topics of analytical and bioanalytical measurement science. Its scope is broad, and ranges from novel measurement platforms and their characterization to multidisciplinary approaches that effectively address important scientific problems. The Editors encourage submissions presenting innovative analytical research in concept, instrumentation, methods, and/or applications, including: mass spectrometry, spectroscopy, and electroanalysis; advanced separations; analytical strategies in “-omics” and imaging, bioanalysis, and sampling; miniaturized devices, medical diagnostics, sensors; analytical characterization of nano- and biomaterials; chemometrics and advanced data analysis.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信