Comparison of epicardial adipose tissue volume of normal and coronary artery disease patients during diastolic and systolic phases of retrospective electrocardiogram-gated volume scan

IF 2.5 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiography Pub Date : 2024-11-30 DOI:10.1016/j.radi.2024.11.018

H. Nakamura , T. Masuda , N. Yui , T. Amano , T. Naoto

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引用次数: 0

Abstract

Introduction

The abundance of epicardial adipose tissue (EAT) correlates with the extent and severity of coronary artery disease (CAD). If the quantity of EAT varies between diastole and systole during an ECG-synchronized volume scan, it can potentially affect the diagnostic accuracy of CAD. The aim of this study was to compare the EAT volume between the diastolic and systolic phases during an ECG-gated volume scan of patients with or without CAD.

Methods

In this study, 47 patients (11 with and 36 without CAD) underwent coronary computed tomography (CT) angiography between September 2022 and August 2023. All patients underwent a second-generation 320-row computed tomography (CT) scan with a retrospective ECG-triggered volume scan. The data volumes obtained at 5 % steps of the R–R interval were automatically analyzed on a Ziostation2 Plus workstation using a CT coronary artery analysis application. Myocardial fat components ranging from −160 to −70 in CT value were extracted to determine fat content. EAT volumes between R–R intervals were compared for 40 % diastolic and 75 % systolic phases in the scans of patients with and without CAD.

Results

The median and interquartile range (IQR) of the EAT volumes were 130 (112–183) mL and 98 (67–129) mL for the groups with and without CAD, respectively, indicating a significant difference (p < 0.05). For the ECG-gated scan without CAD, the median and IQR of the EAT volumes were 98 (66–129) and 94 (68–134) mL in the diastolic and systolic phases (p = 0.82), respectively, and for CAD, 166 (129–191) and 158 (113–178) mL (p = 0.56), respectively. Thus, the differences in the EAT volume were not significant between diastolic and systolic phases (p > 0.05).

Conclusion

Differences in EAT volume between patients with and without CAD were significant. However, the EAT volume differences between the diastolic and systolic phases were not significant, irrespective of CAD, during the ECG-gated volume scans.

Implications for practice

The diastolic and systolic cardiac phases did not significantly influence EAT volume measurements.

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回顾性心电图门控容积扫描正常与冠心病患者舒张期和收缩期心外膜脂肪组织体积的比较

心外膜脂肪组织（EAT）的丰度与冠状动脉疾病（CAD）的范围和严重程度相关。如果在ecg同步容积扫描期间，EAT的数量在舒张期和收缩期之间变化，可能会影响CAD的诊断准确性。本研究的目的是比较有或没有CAD的患者在心电图门控容积扫描时舒张期和收缩期的EAT容积。方法在本研究中，47例患者（11例有CAD， 36例无CAD）于2022年9月至2023年8月接受了冠状动脉计算机断层扫描（CT）血管造影。所有患者都进行了第二代320行CT扫描，并进行了回顾性心电图触发的容积扫描。在Ziostation2 Plus工作站上使用CT冠状动脉分析应用程序自动分析在R-R间隔的5%步获得的数据量。提取CT值为- 160 ~ - 70的心肌脂肪成分，测定脂肪含量。在有和没有CAD的患者的扫描中，比较了40%舒张期和75%收缩期R-R间隔之间的EAT体积。结果冠心病组与非冠心病组的胃容积中位数为130 (112 ~ 183)mL，四分位间距为98 (67 ~ 129)mL，差异有统计学意义(p <；0.05)。对于无CAD的ecg门控扫描，在舒张期和收缩期，EAT容积的中位数和IQR分别为98（66-129）和94 (68-134)mL (p = 0.82)，而对于CAD，分别为166（129-191）和158 (113-178)mL （p = 0.56）。因此，舒张期和收缩期的EAT容积差异不显著(p >；0.05)。结论冠心病患者与非冠心病患者的胃食管容积差异显著。然而，与CAD无关，在ecg门控容积扫描期间，舒张期和收缩期之间的EAT容积差异并不显著。心脏舒张期和收缩期对EAT容积测量没有显著影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiography RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.70

自引率

34.60%

发文量

169

审稿时长

63 days

期刊介绍： Radiography is an International, English language, peer-reviewed journal of diagnostic imaging and radiation therapy. Radiography is the official professional journal of the College of Radiographers and is published quarterly. Radiography aims to publish the highest quality material, both clinical and scientific, on all aspects of diagnostic imaging and radiation therapy and oncology.