Beneficial effects of probiotics to flatten the curve of COVID-19 pandemic: A review

Q3 Nursing

Clinical Nutrition Open Science Pub Date : 2024-12-01 DOI:10.1016/j.nutos.2024.11.002

Samira Rabiei , Zinat Kamali , Parmida Jamilian , Parsa Jamilian

{"title":"Beneficial effects of probiotics to flatten the curve of COVID-19 pandemic: A review","authors":"Samira Rabiei , Zinat Kamali , Parmida Jamilian , Parsa Jamilian","doi":"10.1016/j.nutos.2024.11.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>COVID-19 is a newly emerging pathogen responsible for respiratory infections and has caused high morbidity and mortality globally. To date, there is no effective treatment protocol for this virus.</div></div><div><h3>Objectives</h3><div>The current study has reviewed the probable mechanisms involved in relation between probiotic supplementation and corona virus disease. It also has found the most beneficial strains of probiotic in this regard.</div></div><div><h3>Methods</h3><div>Major search engines such as Web of Science, PubMed, Scopus, ScienceDirect, Medline, and Google Scholar have been used for searching English papers and SID, Magiran, and IranMedex for Persian language papers through keywords such as COVID-19, corona virus, probiotic, clinical trials since early 2020 until the end of 2023. Next, we manually reviewed the contents of these articles. Inclusion criteria included clinical trials on both sexes without any comorbidity.</div></div><div><h3>Results</h3><div>Based on the clinical trials that were assessed in this review, we found that probiotics decrease fever, cough, nasal congestion, shortness of breath and diarrhea in patients with corona virus disease. Furthermore, remission and modification of main symptoms of disease occur sooner in patients who receive oral bacterio therapy compared to those who receive only drug regimen. It also seems that probiotic supplementation not only can reduce requirement to use mechanical ventilation in patients, but also decrease the mortality rate caused by disease. One of the interesting findings of this review is that the most beneficial effects of bacterio therapy, could be attributed to Bifidobacterium and Lactobacillus genus.</div></div><div><h3>Conclusions</h3><div>Consuming probiotics against coronavirus seems promising in prevention and treatment. Probiotics' health and safety benefits have been confirmed, including their role in fighting certain viral infections. Further research is needed to confirm their appropriate performance as a new approach to remission COVID-19 viruses.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"58 ","pages":"Pages 348-360"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Nutrition Open Science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667268524001141","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Nursing","Score":null,"Total":0}

引用次数: 0

Abstract

Background

COVID-19 is a newly emerging pathogen responsible for respiratory infections and has caused high morbidity and mortality globally. To date, there is no effective treatment protocol for this virus.

Objectives

The current study has reviewed the probable mechanisms involved in relation between probiotic supplementation and corona virus disease. It also has found the most beneficial strains of probiotic in this regard.

Methods

Major search engines such as Web of Science, PubMed, Scopus, ScienceDirect, Medline, and Google Scholar have been used for searching English papers and SID, Magiran, and IranMedex for Persian language papers through keywords such as COVID-19, corona virus, probiotic, clinical trials since early 2020 until the end of 2023. Next, we manually reviewed the contents of these articles. Inclusion criteria included clinical trials on both sexes without any comorbidity.

Results

Based on the clinical trials that were assessed in this review, we found that probiotics decrease fever, cough, nasal congestion, shortness of breath and diarrhea in patients with corona virus disease. Furthermore, remission and modification of main symptoms of disease occur sooner in patients who receive oral bacterio therapy compared to those who receive only drug regimen. It also seems that probiotic supplementation not only can reduce requirement to use mechanical ventilation in patients, but also decrease the mortality rate caused by disease. One of the interesting findings of this review is that the most beneficial effects of bacterio therapy, could be attributed to Bifidobacterium and Lactobacillus genus.

Conclusions

Consuming probiotics against coronavirus seems promising in prevention and treatment. Probiotics' health and safety benefits have been confirmed, including their role in fighting certain viral infections. Further research is needed to confirm their appropriate performance as a new approach to remission COVID-19 viruses.

查看原文本刊更多论文

益生菌对平坦COVID-19大流行曲线的有益作用：综述

covid -19是一种新出现的呼吸道感染病原体，在全球范围内造成了高发病率和高死亡率。迄今为止，尚无针对这种病毒的有效治疗方案。目的对补充益生菌与冠状病毒病之间的可能机制进行综述。它还发现了在这方面最有益的益生菌菌株。方法自2020年初至2023年底，使用Web of Science、PubMed、Scopus、ScienceDirect、Medline、b谷歌Scholar等主要搜索引擎检索英文论文，SID、Magiran、IranMedex等主要搜索引擎检索波斯语论文，检索关键词为COVID-19、冠状病毒、益生菌、临床试验等。接下来，我们手动审查这些文章的内容。纳入标准包括无任何合并症的两性临床试验。结果根据本综述评估的临床试验，我们发现益生菌可以减轻冠状病毒病患者的发热、咳嗽、鼻塞、呼吸急促和腹泻。此外，与仅接受药物治疗的患者相比，接受口服细菌治疗的患者疾病主要症状的缓解和改变发生得更快。补充益生菌不仅可以减少患者使用机械通气的需求，还可以降低疾病引起的死亡率。这篇综述的一个有趣的发现是，最有益的细菌治疗效果，可归因于双歧杆菌和乳杆菌属。结论食用益生菌抗冠状病毒具有良好的防治效果。益生菌的健康和安全益处已经得到证实，包括它们在对抗某些病毒感染方面的作用。需要进一步的研究来证实它们作为缓解COVID-19病毒的新方法的适当性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊