Regioselective arylation of (het)aryl fragment in 2-(het)aryl-1-methylperimidines under ruthenium catalysis

IF 1.8 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Mendeleev Communications Pub Date : 2024-11-01 DOI:10.1016/j.mencom.2024.10.033

Konstantin E. Shepelenko , Irina G. Gnatiuk , Andrey A. Aleksandrov , Mikhail E. Minyaev , Victor M. Chernyshev

引用次数: 0

Abstract

The ruthenium-catalyzed reaction of 2-(het)aryl-1-methyl- perimidines with aryl bromides proceeds as regioselective CH ortho-arylation of the (het)aryl fragment, perimidine core acting as a directing group. The reaction is selective and tolerates to different functional groups in aryl bromide thus allowing further functionalization of the obtained products.

Abstract Image

查看原文本刊更多论文

钌催化2-(het)芳基-1-甲基亚嘧啶中（het）芳基片段的区域选择性芳化

钌催化2-(het)芳基-1-甲基-亚酰基与芳基溴的反应是（het）芳基片段的区域选择性CH邻芳基化，亚酰基核作为导向基团。该反应具有选择性，对芳基溴中的不同官能团具有耐受性，从而允许得到的产物进一步功能化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Mendeleev Communications 化学-化学综合

CiteScore

3.00

自引率

21.10%

发文量

226

审稿时长

4-8 weeks

期刊介绍： Mendeleev Communications is the journal of the Russian Academy of Sciences, launched jointly by the Academy of Sciences of the USSR and the Royal Society of Chemistry (United Kingdom) in 1991. Starting from 1st January 2007, Elsevier is the new publishing partner of Mendeleev Communications. Mendeleev Communications publishes short communications in chemistry. The journal primarily features papers from the Russian Federation and the other states of the former USSR. However, it also includes papers by authors from other parts of the world. Mendeleev Communications is not a translated journal, but instead is published directly in English. The International Editorial Board is composed of eminent scientists who provide advice on refereeing policy.