Corrigendum to Peanut (Arachis hypogaea L.) seeds and by-products in metabolic syndrome and cardiovascular disorders: A systematic review of clinical studies Phytomedicine 123 (2024) 155170.

IF 6.7 1区 医学 Q1 CHEMISTRY, MEDICINAL
Yandra Cervelim Nunes, Gian de Oliveira Santos, Nathália Mendes Machado, Alda M M B Otoboni, Lucas Fornari Laurindo, Anusha Bishayee, Carmela Fimognari, Anupam Bishayee, Sandra Maria Barbalho
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引用次数: 0

Abstract

Background: Cardiovascular diseases (CVDs) are the leading causes of death worldwide. The main risk factors are hypertension, diabetes, obesity, and increased serum lipids. The peanut (Arachis hypogaea L.), also known as the groundnut, goober, pindar, or monkey nut, belongs to the Fabaceae family and is the fourth most cultivated oilseed in the world. The seeds and skin of peanuts possess a rich phytochemical profile composed of antioxidants, such as phenolic acids, stilbenes, flavonoids, and phytosterols. Peanut consumption can provide numerous health benefits, such as anti-obesity, antidiabetic, antihypertensive, and hypolipidemic effects. Accordingly, peanuts have the potential to treat CVD and counteract its risk factors.

Purpose: This study aims to critically evaluate the effects of peanuts on metabolic syndrome (MetS) and CVD risk factors based on clinical studies.

Method: This review includes studies indexed in MEDLINE-PubMed, COCHRANE, and EMBASE, and the Preferred Reporting Items for a Systematic Review and Meta-Analysis guidelines were adhered to.

Results: Nineteen studies were included and indicated that the consumption of raw peanuts or differing forms of processed foods containing peanut products and phytochemicals could improve metabolic parameters, such as glycemia, insulinemia, glycated hemoglobin, lipids, body mass index, waist circumference, atherogenic indices, and endothelial function.

Conclusion: We propose that this legume and its products be used as a sustainable and low-cost alternative for the prevention and treatment of MetS and CVD. However, further research with larger sample sizes, longer intervention durations, and more diverse populations is needed to understand the full benefit of peanut consumption in MetS and CVD.

更正:花生(Arachis hypogaea L.)种子和副产品在代谢综合征和心血管疾病中的作用:临床研究的系统性回顾 植物药品 123 (2024) 155170。
背景:心血管疾病(CVD)是导致全球死亡的主要原因。主要风险因素是高血压、糖尿病、肥胖和血清脂质增加。花生(Arachis hypogaea L.)又称落花生、鹅掌楸、平达或猴果,属于豆科,是世界上第四大栽培油籽。花生的种子和果皮含有丰富的植物化学物质,包括酚酸、二苯乙烯类、黄酮类和植物甾醇等抗氧化剂。食用花生对健康有诸多益处,如抗肥胖、抗糖尿病、抗高血压和降血脂作用。因此,花生具有治疗心血管疾病和抵消其风险因素的潜力。目的:本研究旨在根据临床研究严格评估花生对代谢综合征(MetS)和心血管疾病风险因素的影响:方法:本综述包括在 MEDLINE-PubMed、COCHRANE 和 EMBASE 中索引的研究,并遵循系统综述和 Meta 分析的首选报告项目指南:结果:共纳入 19 项研究,结果表明,食用生花生或含有花生产品和植物化学物质的不同形式的加工食品可改善代谢指标,如血糖、胰岛素血症、糖化血红蛋白、血脂、体重指数、腰围、致动脉粥样硬化指数和内皮功能:我们建议将这种豆类及其产品作为预防和治疗代谢性疾病和心血管疾病的一种可持续的低成本替代品。然而,要了解食用花生对代谢综合征和心血管疾病的全部益处,还需要进行样本量更大、干预时间更长、人群更多样化的进一步研究。
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来源期刊
Phytomedicine
Phytomedicine 医学-药学
CiteScore
10.30
自引率
5.10%
发文量
670
审稿时长
91 days
期刊介绍: Phytomedicine is a therapy-oriented journal that publishes innovative studies on the efficacy, safety, quality, and mechanisms of action of specified plant extracts, phytopharmaceuticals, and their isolated constituents. This includes clinical, pharmacological, pharmacokinetic, and toxicological studies of herbal medicinal products, preparations, and purified compounds with defined and consistent quality, ensuring reproducible pharmacological activity. Founded in 1994, Phytomedicine aims to focus and stimulate research in this field and establish internationally accepted scientific standards for pharmacological studies, proof of clinical efficacy, and safety of phytomedicines.
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