Ultrasound-Assisted Extraction of Alginate from Fucus vesiculosus Seaweed By-Product Post-Fucoidan Extraction.

IF 4.9 2区医学 Q1 CHEMISTRY, MEDICINAL

Marine Drugs Pub Date : 2024-11-14 DOI:10.3390/md22110516

Viruja Ummat, Ming Zhao, Saravana Periaswamy Sivagnanam, Shanmugapriya Karuppusamy, Henry Lyons, Stephen Fitzpatrick, Shaba Noore, Dilip K Rai, Laura G Gómez-Mascaraque, Colm O'Donnell, Anet Režek Jambark, Brijesh Kumar Tiwari

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引用次数: 0

Abstract

The solid phase byproduct obtained after conventional fucoidan extraction from the brown seaweed Fucus vesiculosus can be used as a source containing alginate. This study involves ultrasound-assisted extraction (UAE) of alginate from the byproduct using sodium bicarbonate. Response surface methodology (RSM) was applied to obtain the optimum conditions for alginate extraction. The ultrasound (US) treatments included 20 kHz of frequency, 20-91% of amplitude, and an extraction time of 6-34 min. The studied investigated the crude alginate yield (%), molecular weight, and alginate content (%) of the extracts. The optimum conditions for obtaining alginate with low molecular weight were found to be 69% US amplitude and sonication time of 30 min. The alginate extracts obtained were characterized using Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). Ultrasound-assisted extraction involving a short treatment lasting 6-34 min was found to be effective in extracting alginate from the byproduct compared to the conventional extraction of alginate using stirring at 415 rpm and 60 °C for 24 h. The US treatments did not adversely impact the alginate obtained, and the extracted alginates were found to have similar characteristics to the alginate obtained from conventional extraction and commercial sodium alginate.

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超声波辅助从褐藻糖胶提取后的岩藻海藻副产品中提取海藻酸。

从褐色海藻 Fucus vesiculosus 中进行传统褐藻糖胶提取后得到的固相副产品可用作含有海藻酸的来源。本研究使用碳酸氢钠从副产品中超声辅助提取（UAE）海藻酸。应用响应面法（RSM）获得提取海藻酸的最佳条件。超声（US）处理的频率为 20 kHz，振幅为 20-91%，萃取时间为 6-34 分钟。研究调查了提取物的粗海藻酸产量（%）、分子量和海藻酸含量（%）。研究发现，获得低分子量海藻酸的最佳条件是 US 振幅为 69%，超声时间为 30 分钟。傅立叶变换红外光谱（FTIR）、热重分析（TGA）和差示扫描量热法（DSC）对获得的海藻酸提取物进行了表征。与在 415 rpm 和 60 °C 下搅拌 24 h 从副产品中提取海藻酸盐的传统提取方法相比，超声辅助提取（持续 6-34 min 的短时间处理）被认为能有效地从副产品中提取海藻酸盐。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Marine Drugs 医学-医药化学

CiteScore

9.60

自引率

14.80%

发文量

671

审稿时长

1 months

期刊介绍： Marine Drugs (ISSN 1660-3397) publishes reviews, regular research papers and short notes on the research, development and production of drugs from the sea. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible, particularly synthetic procedures and characterization information for bioactive compounds. There is no restriction on the length of the experimental section.