Mia Strohm, Amro Daboul, Anne Obst, Antoine Weihs, Chia-Jung Busch, Thomas Bremert, Jochen Fanghänel, Tatyana Ivanovska, Ingo Fietze, Thomas Penzel, Ralf Ewert, Markus Krüger
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引用次数: 0
Abstract
Background: This study examines the relationship between obstructive sleep apnea severity, sleep position, and body weight, particularly focusing on the negative impact of sleeping in a supine position combined with being overweight in a population-based sample.
Methods: The Apnea-Hypopnea Index (AHI) was utilized as a marker of OSA severity and sleep position from a standardized overnight polysomnography. Participants were categorized by body mass index (BMI) (kg/m2) into normal weight/underweight (<25) and overweight (≥25).
Results and conclusions: The results indicated a higher mean Apnea-Hypopnea Index for those sleeping in the supine position compared to other positions, with overweight individuals experiencing a proportionally greater impact from sleep position than their normal-weight counterparts.
背景：本研究探讨了阻塞性睡眠呼吸暂停的严重程度、睡眠姿势和体重之间的关系，尤其关注仰卧位睡眠和超重对人群的负面影响：方法：利用呼吸暂停-高通气指数（AHI）作为 OSA 严重程度和睡眠姿势的标志，该指标来自标准化的夜间多导睡眠图。根据体重指数（BMI）（kg/m2）将参与者分为正常体重/过轻体重（结果和结论：结果表明，仰卧位睡眠者的平均呼吸暂停-低通气指数高于其他体位，超重者受睡眠体位影响的比例高于体重正常者。
期刊介绍：
Journal of Personalized Medicine (JPM; ISSN 2075-4426) is an international, open access journal aimed at bringing all aspects of personalized medicine to one platform. JPM publishes cutting edge, innovative preclinical and translational scientific research and technologies related to personalized medicine (e.g., pharmacogenomics/proteomics, systems biology). JPM recognizes that personalized medicine—the assessment of genetic, environmental and host factors that cause variability of individuals—is a challenging, transdisciplinary topic that requires discussions from a range of experts. For a comprehensive perspective of personalized medicine, JPM aims to integrate expertise from the molecular and translational sciences, therapeutics and diagnostics, as well as discussions of regulatory, social, ethical and policy aspects. We provide a forum to bring together academic and clinical researchers, biotechnology, diagnostic and pharmaceutical companies, health professionals, regulatory and ethical experts, and government and regulatory authorities.
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