Context-dependency of the REM sleep behavior disorder screening questionnaire - Clinical utility under scrutiny

IF 3.1 3区医学 Q2 CLINICAL NEUROLOGY

Parkinsonism & related disorders Pub Date : 2024-11-17 DOI:10.1016/j.parkreldis.2024.107211

Sinah Röttgen , Christopher E.J. Doppler , Aline Seger , Elke Kalbe , Gereon R. Fink , Michael Sommerauer , Anja Ophey

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引用次数: 0

Abstract

Introduction

The REM Sleep Behavior Disorder (RBD) Screening Questionnaire (RBDSQ) is a widely established screening tool for detecting isolated RBD (iRBD). However, its accuracy may depend on its application context, e.g., the individuals’ awareness of their RBD status. The present work aims to describe the context-dependency and retest reliability of the RBDSQ in an iRBD cohort setting.

Methods

Ninety-four individuals with video-polysomnography confirmed iRBD answered the RBDSQ during pre-polysomnography screening (V0) and post-diagnosis (V1).

Results

The RBDSQ total score significantly differed between V0 and V1 (F(1,92) = 8.02, p = .006, η_p² = 0.019). The intraclass correlation coefficient (ICC_2,1) of the RBDSQ showed moderate reliability between consecutive timepoints (^V0-V1ICC_2,1 = 0.544). The highest Cohen's κ was reached for items 5, 6.3, 6.4, 8, and 9 across timepoint comparisons (0.409 ≤ Cohen's κ ≤ 0.660).

Conclusion

Our findings underscore the context-dependency of the RBDSQ and fluctuations in self-awareness of sleep-related behaviors, necessitating a critical appraisal of questionnaire-based RBD screening tools. Future studies should explore strategies to improve the reliability and accuracy of RBD screening tools, considering the dynamic nature of sleep-related behavior.

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快速眼动睡眠行为障碍筛查问卷的情境依赖性--临床实用性受到质疑

导言快速眼动睡眠行为障碍（RBD）筛查问卷（RBDSQ）是一种广泛使用的筛查工具，用于检测孤立性 RBD（iRBD）。然而，它的准确性可能取决于其应用情境，例如个人对其 RBD 状态的认知。本研究旨在描述 RBDSQ 在 iRBD 队列环境中的情境依赖性和重测可靠性。方法94 名经视频多导睡眠图确诊为 iRBD 的患者在多导睡眠图筛查前（V0）和诊断后（V1）回答了 RBDSQ。RBDSQ 的类内相关系数 (ICC2,1) 显示，连续时间点之间的可靠性适中（V0-V1ICC2,1 = 0.544）。结论我们的研究结果强调了 RBDSQ 的情境依赖性和睡眠相关行为自我意识的波动性，因此有必要对基于问卷的 RBD 筛查工具进行批判性评估。考虑到睡眠相关行为的动态性，未来的研究应探索提高RBD筛查工具可靠性和准确性的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Parkinsonism & related disorders 医学-临床神经学

CiteScore

6.20

自引率

4.90%

发文量

292

审稿时长

39 days

期刊介绍： Parkinsonism & Related Disorders publishes the results of basic and clinical research contributing to the understanding, diagnosis and treatment of all neurodegenerative syndromes in which Parkinsonism, Essential Tremor or related movement disorders may be a feature. Regular features will include: Review Articles, Point of View articles, Full-length Articles, Short Communications, Case Reports and Letter to the Editor.