{"title":"Selenium nanoparticles stabilized with Tween 80: Synthesis, characterization, and application in fortified milk and fermented dairy products","authors":"Andrey Blinov , Andrey Nagdalian , Alexander Serov , Anastasiya Blinova , Zafar Rekhman , Alexey Gvozdenko , Alexey Golik , Alina Askerova , Maxim Pirogov , Maxim Kolodkin , Seid Mahdi Jafari","doi":"10.1016/j.colsurfa.2024.135822","DOIUrl":null,"url":null,"abstract":"<div><div>This study presents the synthesis selenium nanoparticles (SeNPs), stabilized with Tween-80 (Tw) for potential fortification of milk and fermented dairy products. SeNPs were prepared by chemical reduction with ascorbic acid in an aqueous medium. Optimal synthesis parameters were obtained using neural network optimization. Quantum chemical modeling showed that the Se-Tw interaction is an energetically favorable process (<em>∆E</em> < −80 kcal/mol), and the Se-Tw molecular complex is chemically stable (η = 0.078 eV). In turn, the stability of SeNPs was tested by forming solutions with different pH and ionic strength values. It was found that SeNPs stabilized with Tw (SeNPs-Tw) have a negligible effect on the physicochemical parameters of the dispersed phase of milk. A slight increase in titrated acidity by 1–3 °T and a decrease in pH by 0.05–0.12 were detected in experimental milk samples. during 21-days storage. Surprisingly, addition of SeNPs increased the average hydrodynamic radius of disperse composition of milk with 1.5, 2.5 and 3.2 % fat from 24 to 27 nm to 37–38 nm. It is worth noting that titratable acidity increased smoothly in all presented samples and to 120 ± 10 °T, which is in the required range for fermented dairy products. Interestingly, SeNPs-Tw had a stimulating effect on the growth of lactic acid bacteria. Thus, the number of <em>L. acidophilus</em> was higher in the experimental sample with a maximum at SeNPs-Tw concentration equivalent to 30 % of Se recommended daily allowance. Consequently, functional fermented milk products fortified with SeNPs-Tw can potentially become a solution to the problem of a colossal Se deficiency.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"706 ","pages":"Article 135822"},"PeriodicalIF":4.9000,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0927775724026864","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
This study presents the synthesis selenium nanoparticles (SeNPs), stabilized with Tween-80 (Tw) for potential fortification of milk and fermented dairy products. SeNPs were prepared by chemical reduction with ascorbic acid in an aqueous medium. Optimal synthesis parameters were obtained using neural network optimization. Quantum chemical modeling showed that the Se-Tw interaction is an energetically favorable process (∆E < −80 kcal/mol), and the Se-Tw molecular complex is chemically stable (η = 0.078 eV). In turn, the stability of SeNPs was tested by forming solutions with different pH and ionic strength values. It was found that SeNPs stabilized with Tw (SeNPs-Tw) have a negligible effect on the physicochemical parameters of the dispersed phase of milk. A slight increase in titrated acidity by 1–3 °T and a decrease in pH by 0.05–0.12 were detected in experimental milk samples. during 21-days storage. Surprisingly, addition of SeNPs increased the average hydrodynamic radius of disperse composition of milk with 1.5, 2.5 and 3.2 % fat from 24 to 27 nm to 37–38 nm. It is worth noting that titratable acidity increased smoothly in all presented samples and to 120 ± 10 °T, which is in the required range for fermented dairy products. Interestingly, SeNPs-Tw had a stimulating effect on the growth of lactic acid bacteria. Thus, the number of L. acidophilus was higher in the experimental sample with a maximum at SeNPs-Tw concentration equivalent to 30 % of Se recommended daily allowance. Consequently, functional fermented milk products fortified with SeNPs-Tw can potentially become a solution to the problem of a colossal Se deficiency.
期刊介绍:
Colloids and Surfaces A: Physicochemical and Engineering Aspects is an international journal devoted to the science underlying applications of colloids and interfacial phenomena.
The journal aims at publishing high quality research papers featuring new materials or new insights into the role of colloid and interface science in (for example) food, energy, minerals processing, pharmaceuticals or the environment.