Vertebral Bone Quality Score as a Predictor of Subsequent Fractures After Cement Augmentation for Osteoporotic Vertebral Compression Fracture.

IF 3.9 2区医学 Q1 CLINICAL NEUROLOGY

Neurosurgery Pub Date : 2025-06-01 Epub Date: 2024-11-26 DOI:10.1227/neu.0000000000003282

Yu-Cheng Yeh, Mu-Ze Chen, Yung-Hsueh Hu, Ping-Yeh Chiu, Fu-Cheng Kao, Ming-Kai Hsieh, Chia-Wei Yu, Tsung-Ting Tsai, Chi-Chien Niu, Lih-Huei Chen, Wen-Jer Chen, Po-Liang Lai

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引用次数: 0

Abstract

Background and objectives: Dual-energy X-ray absorptiometry (DXA) T -scores have been shown to predict fragility fractures in population-based studies. Recently, a novel MRI-based vertebral bone quality (VBQ) score has been proposed, showing better predictability for fragility fractures compared with DXA T -scores. The aim of this study was to explore the correlation between VBQ scores and DXA T -scores and to determine the impact of VBQ scores on the risk of subsequent fragility fractures after cement augmentation for osteoporotic vertebral compression fracture (OVCF).

Methods: Between January and December 2018, 251 consecutive patients who received cement augmentation for OVCF were included in the study. VBQ scores were calculated using noncontrast T1-weighted MRI. Correlations between VBQ and T -scores were assessed. Patients were divided into 2 groups based on the presence or absence of subsequent fragility fractures after cement augmentation: (1) no Subsequent fracture group and (2) subsequent fracture group. Comparisons between the groups were conducted, and risk factors of subsequent fractures were evaluated using multivariable logistic regression analysis.

Results: Of the patients, 42 (16.7%) experienced subsequent fractures after cement augmentation. The VBQ score showed moderate correlations with the T -score of the hip (r = -0.523, P < .001) and the T -score of the lumbar spine (r = -0.383, P < .001). The subsequent fracture group had a significantly higher VBQ score (4.02 ± 0.56 vs 3.52 ± 0.62, P < .001) and a worse T -score of hip (-3.06 ± 1.28 vs -2.42 ± 0.98, P = .004). In the multivariable analysis, the VBQ score was the only independent predictor of subsequent fractures with 2.799 odds ratio (1.342 to 5.841, P = .006).

Conclusion: In patients who received cement augmentation for OVCF, the VBQ score is significantly correlated with the DXA T -score and may be a more reliable predictor of subsequent fragility fractures.

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作为骨质疏松性椎体压缩骨折骨水泥增强术后继发骨折预测因子的椎体骨质量评分

背景和目的：在基于人群的研究中，双能 X 射线吸收测量（DXA）T 评分已被证明可预测脆性骨折。最近，一种基于磁共振成像的新型椎骨质量（VBQ）评分被提出，与 DXA T 评分相比，该评分显示出对脆性骨折更好的预测能力。本研究旨在探讨VBQ评分与DXA T-scores之间的相关性，并确定VBQ评分对骨质疏松性椎体压缩骨折（OVCF）骨水泥增量术后后续脆性骨折风险的影响：2018年1月至12月期间，研究纳入了251名连续接受骨水泥增量术治疗OVCF的患者。使用非对比T1加权磁共振成像计算VBQ评分。评估了 VBQ 和 T 评分之间的相关性。根据骨水泥增强后是否出现后续脆性骨折，将患者分为两组：(1) 无后续骨折组和 (2) 后续骨折组。对两组患者进行比较，并使用多变量逻辑回归分析评估后续骨折的风险因素：结果：患者中有 42 人（16.7%）在骨水泥增强术后出现后续骨折。VBQ 评分与髋关节 T 评分（r = -0.523，P < .001）和腰椎 T 评分（r = -0.383，P < .001）呈中度相关。后续骨折组的 VBQ 评分明显更高（4.02 ± 0.56 vs 3.52 ± 0.62，P < .001），髋关节 T 评分更差（-3.06 ± 1.28 vs -2.42 ± 0.98，P = .004）。在多变量分析中，VBQ评分是后续骨折的唯一独立预测因素，其几率比为2.799（1.342至5.841，P = .006）：结论：在接受骨水泥增强治疗的 OVCF 患者中，VBQ 评分与 DXA T 评分显著相关，可能是预测后续脆性骨折的更可靠指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurosurgery 医学-临床神经学

CiteScore

8.20

自引率

6.20%

发文量

898

审稿时长

2-4 weeks

期刊介绍： Neurosurgery, the official journal of the Congress of Neurological Surgeons, publishes research on clinical and experimental neurosurgery covering the very latest developments in science, technology, and medicine. For professionals aware of the rapid pace of developments in the field, this journal is nothing short of indispensable as the most complete window on the contemporary field of neurosurgery. Neurosurgery is the fastest-growing journal in the field, with a worldwide reputation for reliable coverage delivered with a fresh and dynamic outlook.