Successful use of PRGF-endoret® and ILM peeling for full thickness macular hole in MacTel type 2: A case report and review of literature.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

European Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-11-26 DOI:10.1177/11206721241301933

Yann Bertolani, Albert Arnaiz-Camacho, Jorge Fernández-Engroba, Jose García-Arumí, Miguel-Ángel Zapata

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引用次数: 0

Abstract

Purpose: To describe the successful use of plasma rich in growth factors (PRGF-Endoret®) and internal limiting membrane peeling for full thickness macular hole in Macular Telangiectasia type 2.

Case presentation: A case report of a full thickness macular hole (FTMH) associated with Macular Telangiectasia (MacTel) type 2 is described. 25-G vitrectomy with internal limiting membrane (ILM) peeling and use of (PRGF-Endoret®) was performed. Several ophthalmological visits were conducted and multiple diagnostic tests were carried out including optical coherence tomography (OCT) and fluorescein angiography. A 72-year-old man under follow-up for MacTel type 2 presented with worsening vision in his left eye, with a best visual corrected acuity (BVCA) of 20/80. OCT demonstrated a FTMH in the left eye measuring 264 µm. A 25-gauge pars plana vitrectomy surgery was performed with ILM peeling, use of PRGF-Endoret® and tamponade with 20% sulfur hexafluoride (SF6). Three weeks after surgery, complete anatomical closure was observed with a BVCA of 20/40, which improved to 20/25 one year after the surgery.

Conclusions: The use of PRGF associated with ILM peeling may be a useful tool in the treatment of macular holes associated with MacTel Type 2 with excellent anatomical and functional outcomes.

查看原文本刊更多论文

成功使用 PRGF-endoret® 和 ILM 剥离术治疗 MacTel 2 型全厚黄斑孔：病例报告和文献综述。

目的：描述富含生长因子的血浆（PRGF-Endoret®）和内缘膜剥离术成功用于治疗 2 型黄斑部远端血管扩张症的全厚黄斑孔：本病例报告了一例与黄斑远端血管扩张症（MacTel）2型相关的全厚黄斑孔（FTMH）。患者接受了 25 G 玻璃体切除术，并进行了内缘膜（ILM）剥离和使用（PRGF-Endoret®）。患者接受了多次眼科检查，并进行了多种诊断测试，包括光学相干断层扫描（OCT）和荧光素血管造影。一名接受 MacTel 2 型随访的 72 岁男子左眼视力恶化，最佳矫正视力（BVCA）为 20/80。OCT 显示左眼的 FTMH 为 264 微米。医生为他实施了25号玻璃体旁切除手术，剥离了ILM，使用了PRGF-Endoret®，并用20%的六氟化硫（SF6）进行了填塞。术后三周，观察到解剖结构完全闭合，BVCA 为 20/40，术后一年改善到 20/25：使用PRGF联合ILM剥离术可能是治疗与MacTel 2型相关的黄斑孔的有效工具，具有良好的解剖和功能效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Ophthalmology 医学-眼科学

CiteScore

3.60

自引率

0.00%

发文量

372

审稿时长

3-8 weeks

期刊介绍： The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.