Copy number alterations in normal breast tissues revealed by single-cell whole-genome sequencing

IF 31.7 1区生物学 Q1 GENETICS & HEREDITY

Nature genetics Pub Date : 2024-11-26 DOI:10.1038/s41588-024-02018-9

引用次数: 0

Abstract

Using single-cell whole-genome sequencing, we reveal the landscape of copy number alterations in normal breast tissue from both BRCA carriers and wild-type individuals.

Abstract Image

查看原文本刊更多论文

单细胞全基因组测序揭示正常乳腺组织中的拷贝数变化

通过单细胞全基因组测序，我们揭示了 BRCA 携带者和野生型个体的正常乳腺组织中拷贝数改变的情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature genetics 生物-遗传学

CiteScore

43.00

自引率

2.60%

发文量

241

审稿时长

3 months

期刊介绍： Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. Integrative genetic topics comprise, but are not limited to: -Genes in the pathology of human disease -Molecular analysis of simple and complex genetic traits -Cancer genetics -Agricultural genomics -Developmental genetics -Regulatory variation in gene expression -Strategies and technologies for extracting function from genomic data -Pharmacological genomics -Genome evolution