The Acceptability and Effects of Internet-Based Cognitive Behavioral Therapy on Depressive Symptoms and Remission in 13- to 17-Year-Old Adolescents: A Systematic Review and Meta-Analysis.

IF 3.6 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of Evidence‐Based Medicine Pub Date : 2024-11-24 DOI:10.1111/jebm.12657

Pei Liu, Mingjing Situ, Xiaoxia Duan, Huan Sun, Meiwen Wang, Yujie Tao, Tingting Luo, Sixun Li, Zhuo Wang, Yi Huang

{"title":"The Acceptability and Effects of Internet-Based Cognitive Behavioral Therapy on Depressive Symptoms and Remission in 13- to 17-Year-Old Adolescents: A Systematic Review and Meta-Analysis.","authors":"Pei Liu, Mingjing Situ, Xiaoxia Duan, Huan Sun, Meiwen Wang, Yujie Tao, Tingting Luo, Sixun Li, Zhuo Wang, Yi Huang","doi":"10.1111/jebm.12657","DOIUrl":null,"url":null,"abstract":"Objective: This study aimed to evaluate the acceptability and effects of internet-based cognitive behavioral therapy (iCBT) or CBT-oriented interventions compared with control groups on depressive symptoms, remission of depression, and quality of life (QOL) in adolescents.Methods: We searched English and Chinese databases for randomized controlled trials up to October 10, 2024 that investigated the effects of iCBT compared with controls in adolescents exhibiting elevated depressive symptoms or diagnosed with depression. Standardized mean differences (SMDs), relative risks (RRs), and 95% confidence intervals were applied to evaluate the pooled effects of outcomes.Results: A total of 19 RCTs involving 3574 cases were included in this study. We found small effects on depressive symptoms severity at different time points (posttest: SMD = -0.49 [-0.66, -0.33]; 3-month follow-up [FU3]: SMD = -0.21 [-0.30, -0.11]; FU6: SMD = -0.18 [-0.35, -0.02]; FU12: SMD = -0.38 [-0.56, -0.20]). We also found a significant effect in depression remission rate at the posttest (RR = 1.74 [1.36, 2.21]) and a significant effect in QOL at the posttest (SMD = 0.30 [0.07, 0.54]). However, the result regarding acceptability was nonsignificant (RR = 1.22 [0.76, 1.97]). No significant publication bias was found in these results.Conclusion: iCBT or internet-based CBT-oriented interventions can effectively reduce depressive symptom severity and improve depression remission rate and QOL in depressed adolescents. These results are preliminary and require further validation through future systematic reviews.","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":" ","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Evidence‐Based Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/jebm.12657","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study aimed to evaluate the acceptability and effects of internet-based cognitive behavioral therapy (iCBT) or CBT-oriented interventions compared with control groups on depressive symptoms, remission of depression, and quality of life (QOL) in adolescents.

Methods: We searched English and Chinese databases for randomized controlled trials up to October 10, 2024 that investigated the effects of iCBT compared with controls in adolescents exhibiting elevated depressive symptoms or diagnosed with depression. Standardized mean differences (SMDs), relative risks (RRs), and 95% confidence intervals were applied to evaluate the pooled effects of outcomes.

Results: A total of 19 RCTs involving 3574 cases were included in this study. We found small effects on depressive symptoms severity at different time points (posttest: SMD = -0.49 [-0.66, -0.33]; 3-month follow-up [FU3]: SMD = -0.21 [-0.30, -0.11]; FU6: SMD = -0.18 [-0.35, -0.02]; FU12: SMD = -0.38 [-0.56, -0.20]). We also found a significant effect in depression remission rate at the posttest (RR = 1.74 [1.36, 2.21]) and a significant effect in QOL at the posttest (SMD = 0.30 [0.07, 0.54]). However, the result regarding acceptability was nonsignificant (RR = 1.22 [0.76, 1.97]). No significant publication bias was found in these results.

Conclusion: iCBT or internet-based CBT-oriented interventions can effectively reduce depressive symptom severity and improve depression remission rate and QOL in depressed adolescents. These results are preliminary and require further validation through future systematic reviews.

查看原文本刊更多论文

基于互联网的认知行为疗法对 13-17 岁青少年抑郁症状和缓解的可接受性及效果：系统回顾与元分析》。

研究目的本研究旨在评估基于互联网的认知行为疗法（iCBT）或以 CBT 为导向的干预措施与对照组相比，对青少年抑郁症状、抑郁症缓解和生活质量（QOL）的可接受性和效果：我们在中英文数据库中检索了截至 2024 年 10 月 10 日的随机对照试验，这些试验研究了 iCBT 与对照组相比对表现出抑郁症状升高或确诊为抑郁症的青少年的影响。采用标准化均值差异（SMDs）、相对风险（RRs）和95%置信区间来评估结果的集合效应：本研究共纳入了 19 项 RCT，涉及 3574 个病例。我们发现，不同时间点对抑郁症状严重程度的影响较小（测试后：SMD = -0.49 [-0.66, -0.33]；3 个月随访 [FU3]：SMD=-0.21[-0.30，-0.11]；FU6：SMD=-0.18[-0.35，-0.02]；FU12：SMD=-0.38[-0.56，-0.20]）。我们还发现，在后测阶段，抑郁症缓解率有显著影响（RR = 1.74 [1.36, 2.21]），在后测阶段，QOL 有显著影响（SMD = 0.30 [0.07, 0.54]）。然而，关于可接受性的结果并不显著（RR = 1.22 [0.76, 1.97]）。结论：iCBT 或基于互联网的 CBT 干预疗法可有效降低抑郁症状的严重程度，提高抑郁症缓解率和青少年的 QOL。这些结果是初步的，需要通过今后的系统综述进一步验证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Evidence‐Based Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

11.20

自引率

1.40%

发文量

期刊介绍： The Journal of Evidence-Based Medicine (EMB) is an esteemed international healthcare and medical decision-making journal, dedicated to publishing groundbreaking research outcomes in evidence-based decision-making, research, practice, and education. Serving as the official English-language journal of the Cochrane China Centre and West China Hospital of Sichuan University, we eagerly welcome editorials, commentaries, and systematic reviews encompassing various topics such as clinical trials, policy, drug and patient safety, education, and knowledge translation.