Regenerative Potential of PDL-Derived Small Extracellular Vesicles

IF 3.4 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of periodontal research Pub Date : 2024-11-24 DOI:10.1111/jre.13356

Anahid A. Birjandi, Steven Lynham, Eva Matalova, Mandeep Ghuman, Paul Sharpe

引用次数: 0

Abstract

Treatment of gingival fibroblasts with PDL extracellular vesicles results in promotion of Wnt signalling pathway and osteogenic differentiation. PDL secretome shows selective wound healing and matrix remodelling which can have implications for future periodontal regenerative strategies.

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PDL衍生的细胞外小泡的再生潜力

用 PDL 细胞外囊泡处理牙龈成纤维细胞可促进 Wnt 信号通路和成骨分化。PDL 分泌物组显示出选择性伤口愈合和基质重塑作用，这对未来的牙周再生策略具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of periodontal research 医学-牙科与口腔外科

CiteScore

6.90

自引率

5.70%

发文量

103

审稿时长

6-12 weeks

期刊介绍： The Journal of Periodontal Research is an international research periodical the purpose of which is to publish original clinical and basic investigations and review articles concerned with every aspect of periodontology and related sciences. Brief communications (1-3 journal pages) are also accepted and a special effort is made to ensure their rapid publication. Reports of scientific meetings in periodontology and related fields are also published. One volume of six issues is published annually.