Validation of the Quick Mild Cognitive Impairment Screen in an American Sample of Patients With Mild Cognitive Impairment and Mild Dementia

IF 3.6 3区医学 Q2 GERIATRICS & GERONTOLOGY

International Journal of Geriatric Psychiatry Pub Date : 2024-11-25 DOI:10.1002/gps.70026

Dariella A. Fernandez, Suzanne Schmitz, Heather Foil, Robert Brouillette, Jeffrey N. Keller, Robin C. Hilsabeck

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引用次数: 0

Abstract

Objective

Early detection of cognitive impairment is critical for patient outcomes, yet cognitive impairment is under identified in primary care settings largely due to time constraints. The Quick Mild Cognitive Impairment (Qmci) screen was developed to address the need for a short cognitive screening instrument (< 5 min) that is sensitive to early cognitive change but has not been validated in the United States (US). The objective of this study was to examine the classification accuracy of the Qmci in participants from two memory specialty (e.g., secondary outpatient) clinics in the US.

Methods

Participants were 152 older adults: 87 participants were cognitively normal (CN), 48 were diagnosed with mild cognitive impairment (MCI) and 17 were diagnosed with mild dementia (DEM). Classification accuracy of the Qmci and Mini Mental State Examination (MMSE) were compared in participants with and without cognitive impairment.

Results

The Qmci demonstrated higher classification accuracy in differentiating CN from cognitively impaired participants (i.e., MCI and DEM) (AUC = 0.82) than the MMSE (AUC = 0.77). The optimal cut-off score for the Qmci was < 67, which achieved a sensitivity of 79% and specificity of 80%. The optimal MMSE cut-off score was < 27, which achieved a sensitivity of 97% and specificity of 43%.

Conclusions

The Qmci is a valid cognitive screening instrument for detecting early stages of cognitive impairment in memory clinic samples in the US. Its short administration time and increased specificity for detecting MCI make it an attractive option for use in primary care settings. Further validation of the Qmci is needed, specifically within primary care settings.

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在美国轻度认知障碍和轻度痴呆患者样本中验证轻度认知障碍快速筛查结果

目标认知功能障碍的早期检测对患者的预后至关重要，但主要由于时间限制，初级医疗机构对认知功能障碍的识别不足。开发轻度认知功能障碍快速筛查（Qmci）的目的是为了满足对一种对早期认知功能变化敏感的简短认知筛查工具（5 分钟）的需求，但该工具尚未在美国得到验证。本研究的目的是对美国两家记忆专科（如二级门诊）诊所的参与者进行Qmci分类准确性的检测。方法参与者为 152 名老年人：其中 87 人认知能力正常 (CN)，48 人被诊断为轻度认知障碍 (MCI)，17 人被诊断为轻度痴呆 (DEM)。在有认知障碍和无认知障碍的参与者中比较了 Qmci 和迷你精神状态检查 (MMSE) 的分类准确性。结果 Qmci 在区分 CN 与认知障碍参与者（即 MCI 和 DEM）方面的分类准确性（AUC = 0.82）高于 MMSE（AUC = 0.77）。Qmci 的最佳临界值为 <67，灵敏度为 79%，特异度为 80%。MMSE 的最佳临界值为 27 分，灵敏度为 97%，特异度为 43%。结论 Qmci 是一种有效的认知筛查工具，可用于检测美国记忆诊所样本中早期认知障碍的情况。它的使用时间短，检测 MCI 的特异性更高，因此在初级医疗机构中使用非常有吸引力。Qmci 还需要进一步验证，特别是在初级医疗机构中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Geriatric Psychiatry 医学-精神病学

CiteScore

6.10

自引率

2.50%

发文量

168

审稿时长

4-8 weeks

期刊介绍： The rapidly increasing world population of aged people has led to a growing need to focus attention on the problems of mental disorder in late life. The aim of the Journal is to communicate the results of original research in the causes, treatment and care of all forms of mental disorder which affect the elderly. The Journal is of interest to psychiatrists, psychologists, social scientists, nurses and others engaged in therapeutic professions, together with general neurobiological researchers. The Journal provides an international perspective on the important issue of geriatric psychiatry, and contributions are published from countries throughout the world. Topics covered include epidemiology of mental disorders in old age, clinical aetiological research, post-mortem pathological and neurochemical studies, treatment trials and evaluation of geriatric psychiatry services.