Dosimetry for FLASH and other non-standard radiotherapy sources

IF 1.6 3区物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY

Radiation Measurements Pub Date : 2024-11-08 DOI:10.1016/j.radmeas.2024.107330

Duncan J. Butler , Micah Barnes , Malcolm R. McEwen , Michael L.F. Lerch , Suzie L. Sheehy , Yaw-Ren E. Tan , Ivan M. Williams , Jacinta S.L. Yap

引用次数: 0

Abstract

We review current dosimetry practices for non-standard radiotherapy sources. We classify radiotherapy sources as established, variations of established, or novel. Our review concentrates on novel sources including ultra-high dose-rate (FLASH) sources and some that have yet to be used for clinical radiotherapy. Factors which differentiate non-standard sources include dose-rate, temporal pulse structure, spatial fractionation, focussing, the presence of magnetic fields, and energy range. For the most part we exclude techniques which use materials inside the tumor to modify the dose. Dosimetry techniques include ionization chambers, film, alanine, calorimetry, and solid-state detectors. We review dosimetry only, neglecting other issues such as beam monitoring, patient delivery systems and treatment planning.

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FLASH 和其他非标准放射治疗源的剂量测定

我们回顾了当前非标准放射治疗源的剂量测定方法。我们将放射疗法源分为已确立的放射疗法源、已确立放射疗法源的变体或新型放射疗法源。我们的综述主要针对新型放射源，包括超高剂量率（FLASH）放射源和一些尚未用于临床放射治疗的放射源。区分非标准放射源的因素包括剂量率、时间脉冲结构、空间分割、聚焦、磁场的存在以及能量范围。在大多数情况下，我们不包括使用肿瘤内部材料来改变剂量的技术。剂量测定技术包括电离室、胶片、丙氨酸、热量计和固态探测器。我们只审查剂量测定，而忽略了其他问题，如光束监测、病人输送系统和治疗计划。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiation Measurements 工程技术-核科学技术

CiteScore

4.10

自引率

20.00%

发文量

116

审稿时长

48 days

期刊介绍： The journal seeks to publish papers that present advances in the following areas: spontaneous and stimulated luminescence (including scintillating materials, thermoluminescence, and optically stimulated luminescence); electron spin resonance of natural and synthetic materials; the physics, design and performance of radiation measurements (including computational modelling such as electronic transport simulations); the novel basic aspects of radiation measurement in medical physics. Studies of energy-transfer phenomena, track physics and microdosimetry are also of interest to the journal. Applications relevant to the journal, particularly where they present novel detection techniques, novel analytical approaches or novel materials, include: personal dosimetry (including dosimetric quantities, active/electronic and passive monitoring techniques for photon, neutron and charged-particle exposures); environmental dosimetry (including methodological advances and predictive models related to radon, but generally excluding local survey results of radon where the main aim is to establish the radiation risk to populations); cosmic and high-energy radiation measurements (including dosimetry, space radiation effects, and single event upsets); dosimetry-based archaeological and Quaternary dating; dosimetry-based approaches to thermochronometry; accident and retrospective dosimetry (including activation detectors), and dosimetry and measurements related to medical applications.