Review of real time 2D dosimetry in external radiotherapy: Advancements and techniques

IF 1.6 3区物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY

Radiation Measurements Pub Date : 2024-11-18 DOI:10.1016/j.radmeas.2024.107344

Luana de Freitas Nascimento , Alessia Gasparini

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引用次数: 0

Abstract

The objective of this paper is to provide a comprehensive review of the advancements and techniques in real time two-dimensional (2D) dosimetry for external radiation therapy with emphasis in vivo dosimetry and patient specific quality assurance. External radiation therapy plays a crucial role in cancer treatment, delivering high-energy radiation beams to target tumours while minimizing damage to surrounding healthy tissues. Accurate dosimetry, as both the measurement of the dose and its delivered location, is paramount to ensure effective treatment outcomes and minimize potential side effects.

The planned content of this paper encompasses a thorough examination of the advancements made in 2D dosimetry techniques, including solid state and electronic systems. The evolution from traditional passive dosimetry to modern real time detectors, such as portal imaging, has revolutionized the field, offering enhanced precision, efficiency, and convenience. This review will discuss the principles, advantages, and limitations of these systems, along with their practical implementation and calibration procedures.

Furthermore, the paper will highlight novel technologies, such as luminescence coatings, for quality assurance (QA) and real-time dose verification during treatment. The use of innovative materials and designs in dosemeters, including high spatial resolution detectors and tissue-equivalent phantoms, will also be explored. Additionally, the incorporation of advanced data analysis techniques, such as machine/deep learning algorithms, for dose reconstruction and QA will be addressed.

The review will also explore the application of real time 2D dosimetry in modern clinical and pre-clinical modalities, including intensity-modulated radiation therapy and volumetric modulated arc therapy, stereotactic radiosurgery, image-guided radiation therapy, particle therapy, adaptive radiotherapy, electron and proton ultra-high dose rate therapy and very high energy electrons.

By providing an up-to-date overview of the state-of-the-art in real time 2D dosimetry in vivo dosimetry and patient specific quality assurance, this paper aims to inform and guide professionals in the field, facilitating the adoption of cutting-edge techniques and improving the accuracy and safety of external radiotherapy treatments.

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回顾体外放射治疗中的实时二维剂量测量：进展与技术

本文旨在全面综述体外放射治疗实时二维（2D）剂量测定的进展和技术，重点是体内剂量测定和针对患者的质量保证。体外放射治疗在癌症治疗中起着至关重要的作用，它将高能辐射束射向目标肿瘤，同时最大限度地减少对周围健康组织的损伤。要确保有效的治疗效果并最大限度地减少潜在的副作用，精确的剂量测定（包括剂量及其投射位置的测量）至关重要。本文的计划内容包括对二维剂量测定技术（包括固态和电子系统）所取得的进展进行全面的研究。从传统的被动剂量测定到现代的实时探测器（如门式成像），这一领域发生了革命性的变化，精度、效率和便利性都得到了提高。本文将讨论这些系统的原理、优势和局限性，以及它们的实际应用和校准程序。此外，本文还将重点介绍用于治疗过程中质量保证（QA）和实时剂量验证的新技术，如发光涂层。论文还将探讨剂量计中创新材料和设计的使用，包括高空间分辨率探测器和组织等效模型。综述还将探讨实时二维剂量学在现代临床和临床前模式中的应用，包括调强放射治疗和容积调强弧治疗、立体定向放射外科、图像引导放射治疗、粒子治疗、自适应放射治疗、电子和质子超高剂量率治疗以及高能电子。本文概述了实时二维剂量测定、体内剂量测定和患者特定质量保证方面的最新技术，旨在为该领域的专业人员提供信息和指导，促进尖端技术的采用，提高体外放射治疗的准确性和安全性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiation Measurements 工程技术-核科学技术

CiteScore

4.10

自引率

20.00%

发文量

116

审稿时长

48 days

期刊介绍： The journal seeks to publish papers that present advances in the following areas: spontaneous and stimulated luminescence (including scintillating materials, thermoluminescence, and optically stimulated luminescence); electron spin resonance of natural and synthetic materials; the physics, design and performance of radiation measurements (including computational modelling such as electronic transport simulations); the novel basic aspects of radiation measurement in medical physics. Studies of energy-transfer phenomena, track physics and microdosimetry are also of interest to the journal. Applications relevant to the journal, particularly where they present novel detection techniques, novel analytical approaches or novel materials, include: personal dosimetry (including dosimetric quantities, active/electronic and passive monitoring techniques for photon, neutron and charged-particle exposures); environmental dosimetry (including methodological advances and predictive models related to radon, but generally excluding local survey results of radon where the main aim is to establish the radiation risk to populations); cosmic and high-energy radiation measurements (including dosimetry, space radiation effects, and single event upsets); dosimetry-based archaeological and Quaternary dating; dosimetry-based approaches to thermochronometry; accident and retrospective dosimetry (including activation detectors), and dosimetry and measurements related to medical applications.