Cognitive deficits after COVID-19 associated with brain injury biomarkers and volume loss

IF 58.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Medicine Pub Date : 2024-11-25 DOI:10.1038/s41591-024-03379-8

引用次数: 0

Abstract

A prospective, multicenter study of patients hospitalized with COVID-19 demonstrates objective global cognitive impairment after 12–18 months of follow-up, especially in those who had experienced encephalopathy. The cognitive impairment was associated with increased levels of serum brain injury biomarkers and a reduction in regional brain volume on MRI.

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COVID-19 后的认知障碍与脑损伤生物标志物和体积损失有关

一项针对 COVID-19 住院患者的前瞻性多中心研究显示，经过 12-18 个月的随访，患者的整体认知能力出现了客观损害，尤其是那些曾出现过脑病的患者。认知障碍与血清脑损伤生物标志物水平升高和核磁共振成像显示的区域脑容量减少有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

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