Supercritical fluid extraction of yerba mate: Decaffeination, purification, encapsulation, and controlled release

IF 3.4 3区工程技术 Q2 CHEMISTRY, PHYSICAL

Journal of Supercritical Fluids Pub Date : 2024-11-15 DOI:10.1016/j.supflu.2024.106456

Bruna Sgarioni, Luane C. Angeli, Matheus R. Andrade, Rubem M.F. Vargas, Eduardo Cassel

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引用次数: 0

Abstract

Ilex paraguariensis is a source of bioactive compounds, which have been demonstrated to mitigate neurological disorders and enhance athletic performance. This study aimed to decaffeinate yerba mate using supercritical fluid extraction, followed by caffeine purification. The purified extract was encapsulated in gelatin via spray drying, and its release profile was evaluated in simulated gastric fluid. A mathematical model was established to describe the release behavior of the encapsulated extract. The characterization of yerba mate leaves and extracts was conducted prior to and following purification via HPLC. The capsules were subjected to analysis using SEM, FTIR e TGA, while the release fluid was examined using ultraviolet spectroscopy. The optimized SFE process produced decaffeinated yerba mate and the resulting extract exhibited a caffeine purity of approximately 87 %. The capsules were observed to possess a spherical morphology and micrometric particle size, and the release profile was found to follow a first-order kinetic model.

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超临界流体萃取耶巴马黛茶：去咖啡因、提纯、封装和控释

Ilex paraguariensis 是一种生物活性化合物的来源，已被证明可减轻神经系统疾病和提高运动表现。本研究旨在使用超临界流体萃取法去除耶巴马黛茶中的咖啡因，然后进行咖啡因纯化。纯化后的提取物通过喷雾干燥封装在明胶中，并在模拟胃液中对其释放情况进行了评估。建立了一个数学模型来描述封装提取物的释放行为。在通过高效液相色谱进行纯化之前和之后，对玛黛叶和提取物进行了表征。使用扫描电镜、傅立叶变换红外光谱和热重分析法对胶囊进行了分析，并使用紫外光谱对释放液进行了检测。优化的 SFE 工艺生产出了无咖啡因的耶巴马黛茶，提取物中咖啡因的纯度约为 87%。据观察，胶囊具有球形形态和微米级粒度，释放曲线遵循一阶动力学模型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Supercritical Fluids 工程技术-工程：化工

CiteScore

7.60

自引率

10.30%

发文量

236

审稿时长

56 days

期刊介绍： The Journal of Supercritical Fluids is an international journal devoted to the fundamental and applied aspects of supercritical fluids and processes. Its aim is to provide a focused platform for academic and industrial researchers to report their findings and to have ready access to the advances in this rapidly growing field. Its coverage is multidisciplinary and includes both basic and applied topics. Thermodynamics and phase equilibria, reaction kinetics and rate processes, thermal and transport properties, and all topics related to processing such as separations (extraction, fractionation, purification, chromatography) nucleation and impregnation are within the scope. Accounts of specific engineering applications such as those encountered in food, fuel, natural products, minerals, pharmaceuticals and polymer industries are included. Topics related to high pressure equipment design, analytical techniques, sensors, and process control methodologies are also within the scope of the journal.