Triple threat: Sequential meningitis infections in an immunosuppressed patient with Morganella morganii, Acinetobacter baumannii, and vancomycin-resistant Enterococcus faecium

Abstract

Gram-negative bacilli and vancomycin-resistant enterococci (VRE) are rare causative agents in the etiology of bacterial meningitis and can lead to significant mortality due to the difficulty of treatment. This article reports three successive cases of different meningitis clinical presentations in an immunosuppressed patient diagnosed with diffuse large B-cell lymphoma. A 65-year-old male patient was initially followed with Morganella morganii meningitis. Later, the patient was diagnosed with Acinetobacter meningitis and VRE meningitis. Clinical and microbiological success was achieved following a prolonged hospital stay and antibiotic therapy.