Submillimeter fiber robots capable of decoupled macro-micro motion for endoluminal manipulation

IF 11.7 1区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Cheng Zhou, Zheng Xu, Zecai Lin, Xiaotong Qin, Jingyuan Xia, Xiaojie Ai, Chuqian Lou, Ziyi Huang, Shaoping Huang, Huanghua Liu, Yun Zou, Weidong Chen, Guang-Zhong Yang, Anzhu Gao
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Abstract

Endoluminal and endocavitary intervention via natural orifices of the body is an emerging trend in medicine, further underpinning the future of early intervention and precision surgery. This motivates the development of small continuum robots to navigate freely in confined and tortuous environment. The trade-off between a large range of motion and high precision with concomitant actuation cross-talk poses a major challenge. Here, we present a submillimeter-scale fiber robot (~1 mm) capable of decoupled macro and micro manipulations for intervention and operation. The thin optical fibers, working both as mechanical tendons and light waveguides, can be pulled/pushed to actuate the macro tendon-driven continuum robot and transmit light to actuate the liquid crystal elastomer–based micro built-in light-driven parallel robot. The combination of the decoupled macro and micro motions can accomplish accurate cross-scale motion from several millimeters down to tens of micrometers. In vivo animal studies are performed to demonstrate its positioning accuracy of precise micro operations in endoluminal or endocavitary intervention.
亚毫米级光纤机器人,可进行宏观与微观解耦运动,用于腔内操作。
通过人体自然孔道进行腔内和腔内介入治疗是医学界的一个新兴趋势,为未来的早期介入治疗和精准外科手术奠定了基础。这推动了小型连续机器人的发展,使其能够在狭窄迂回的环境中自由导航。大运动范围和高精度之间的权衡以及随之而来的执行交叉干扰是一项重大挑战。在这里,我们展示了一种亚毫米级光纤机器人(约 1 毫米),它能够进行解耦的宏观和微观操作,以进行干预和操作。纤细的光纤既是机械肌腱,又是光波导,可以通过拉/推来驱动宏观肌腱驱动的连续机器人,也可以通过光传输来驱动基于液晶弹性体的微型内置光驱动并联机器人。宏观和微观运动的解耦组合可以实现从几毫米到几十微米的精确跨尺度运动。体内动物实验证明了它在腔内或腔内介入手术中精确微操作的定位精度。
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来源期刊
Science Advances
Science Advances 综合性期刊-综合性期刊
CiteScore
21.40
自引率
1.50%
发文量
1937
审稿时长
29 weeks
期刊介绍: Science Advances, an open-access journal by AAAS, publishes impactful research in diverse scientific areas. It aims for fair, fast, and expert peer review, providing freely accessible research to readers. Led by distinguished scientists, the journal supports AAAS's mission by extending Science magazine's capacity to identify and promote significant advances. Evolving digital publishing technologies play a crucial role in advancing AAAS's global mission for science communication and benefitting humankind.
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