High-performance gelatin-based hydrogel flexible sensor for respiratory monitoring and human–machine interaction

IF 13.3 1区工程技术 Q1 ENGINEERING, CHEMICAL

Chemical Engineering Journal Pub Date : 2024-11-23 DOI:10.1016/j.cej.2024.157975

Ruonan Liu, Yanpeng Wang, Haoxiang Chu, Yiqi Li, Yehan Li, Yunjun Zhao, Ye Tian, Zhixiu Xia

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引用次数: 0

Abstract

Natural hydrogels like gelatin are ideal for fabricating sensors that monitor human body signals due to their excellent biocompatibility. However, their typically large molecular weight restricts molecular mobility and repositioning under stress, limiting their stretchability performance. In this study, a hydrogel sensor PAM-Gel/β-GP/LiCl (named: PGBL) combining gelatin with ion-complexation, is proposed. Through the synergistic effect of sodium β-glycerophosphate (β-GP) and LiCl, the PAM-gelatin-based hydrogel achieves an extraordinary elongation strain exceeding 11000 %, enabling ultra-stretchability. Additionally, PGBL exhibits excellent electrical conductivity (8.2 S/m), high sensitivity (GF approximately 4.1), and resilience to low temperatures (−24 °C). Moreover, PGBL demonstrates strong adhesion, making it suitable for skin attachment in human body sensing applications. Integrating PGBL hydrogel sensors with a robotic hand has led to the development of a human–machine interaction control system. Furthermore, combining real-time data transmission and visualization technologies has resulted in a real-time respiratory monitoring system, which can monitor sleep apnoea blockage. PGBL hydrogel sensors show promising applications in biomedical fields and biosensing, highlighting their potential in healthcare monitoring systems.

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用于呼吸监测和人机交互的高性能明胶基水凝胶柔性传感器

明胶等天然水凝胶具有良好的生物相容性，是制造人体信号监测传感器的理想材料。然而，它们通常分子量较大，限制了分子的流动性和在应力作用下的重新定位，从而限制了它们的拉伸性能。本研究提出了一种结合明胶与离子络合的水凝胶传感器 PAM-Gel/β-GP/LiCl（命名为 PGBL）。通过 β-甘油磷酸酯钠（β-GP）和氯化锂的协同作用，PAM-明胶基水凝胶实现了超过 11000 % 的超常伸长应变，实现了超拉伸性。此外，PGBL 还具有出色的导电性（8.2 S/m）、高灵敏度（GF 约 4.1）和低温适应性（-24 °C）。此外，PGBL 还具有很强的粘附性，因此适用于人体传感应用中的皮肤附着。将 PGBL 水凝胶传感器与机器人手相结合，开发出了人机交互控制系统。此外，结合实时数据传输和可视化技术，还开发出了实时呼吸监测系统，可监测睡眠呼吸暂停阻塞情况。PGBL 水凝胶传感器在生物医学领域和生物传感方面的应用前景广阔，凸显了其在医疗保健监测系统中的潜力。

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来源期刊

Chemical Engineering Journal 工程技术-工程：化工

CiteScore

21.70

自引率

9.30%

发文量

6781

审稿时长

2.4 months

期刊介绍： The Chemical Engineering Journal is an international research journal that invites contributions of original and novel fundamental research. It aims to provide an international platform for presenting original fundamental research, interpretative reviews, and discussions on new developments in chemical engineering. The journal welcomes papers that describe novel theory and its practical application, as well as those that demonstrate the transfer of techniques from other disciplines. It also welcomes reports on carefully conducted experimental work that is soundly interpreted. The main focus of the journal is on original and rigorous research results that have broad significance. The Catalysis section within the Chemical Engineering Journal focuses specifically on Experimental and Theoretical studies in the fields of heterogeneous catalysis, molecular catalysis, and biocatalysis. These studies have industrial impact on various sectors such as chemicals, energy, materials, foods, healthcare, and environmental protection.