Hormone replacement therapy and non-gynaecological cancers.

Q3 Medicine

Post reproductive health Pub Date : 2024-12-01 Epub Date: 2024-11-21 DOI:10.1177/20533691241304028

Sindhu Sekar, Bid Kumar

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引用次数: 0

Abstract

Background: There is lack of knowledge and awareness about HRT use in non-gynaecological cancer survivors. The decision to advocate or discourage HRT in such women depends on various factors, including cancer type, hormone sensitivity, and individual patient characteristics. The paucity of available good quality clinical evidence and epidemiological data leads to lack of consensus in such cases. This article aims to address this knowledge gap by conducting a comprehensive qualitative analysis of the existing literature pertaining to HRT use in non-gynaecological cancer survivors.

Materials and methods: We conducted a literature review. A systematic review was not possible because of lack of good quality research. We excluded case reports.

Results: A total of 55 papers were identified and all of these have been referenced. We have presented the inconsistencies and uncertainties in the evidence available from the limited information available from cohort studies.

Conclusion: Prescription of HRT in cancer survivors of many hormone dependent non-gynaecological cancers needs careful consideration of histology of the cancer and consideration about liaison with the concerned oncology team.

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激素替代疗法与非妇科癌症。

背景：人们对非妇科癌症幸存者使用 HRT 缺乏了解和认识。是否提倡或阻止此类妇女使用激素替代疗法取决于多种因素，包括癌症类型、激素敏感性和患者的个体特征。由于缺乏高质量的临床证据和流行病学数据，在这种情况下缺乏共识。本文旨在通过对与非妇科癌症幸存者使用激素治疗相关的现有文献进行全面的定性分析，填补这一知识空白：我们进行了文献综述。由于缺乏高质量的研究，因此无法进行系统性综述。我们排除了病例报告：结果：共发现 55 篇论文，所有这些论文都有参考文献。我们从队列研究的有限信息中发现了证据的不一致性和不确定性：结论：对许多激素依赖性非妇科癌症的癌症幸存者开具 HRT 处方时，需要仔细考虑癌症的组织结构，并考虑与相关肿瘤团队的联系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Post reproductive health Medicine-Obstetrics and Gynecology

CiteScore

2.50

自引率

0.00%

发文量

期刊介绍： Post Reproductive Health (formerly Menopause International) is a MEDLINE indexed, peer reviewed source of news, research and opinion. Aimed at all those involved in the field of post reproductive health study and treatment, it is a vital resource for all practitioners and researchers. As the official journal of the British Menopause Society (BMS), Post Reproductive Health has a broad scope, tackling all the issues in this field, including the current controversies surrounding postmenopausal health and an ageing and expanding female population. Initially this journal will concentrate on the key areas of menopause, sexual health, urogynaecology, metabolic bone disease, cancer diagnosis and treatment, recovering from cancer, cardiovascular disease, cognition, prescribing, use of new hormone therapies, psychology, the science of ageing, sociology, economics, and quality of life. However as a progressive and innovative journal the Editors are always willing to consider other areas relevant to this rapidly expanding area of healthcare.